Why does CAS 210880-92-5 appear in more than one EU cosmetic annex?

A substance identified by CAS 210880-92-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 210880-92-5 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 210880-92-5

Q: How do I use CAS 210880-92-5 for compliance screening?

Cross-reference CAS 210880-92-5 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 210880-92-5 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 210880-92-5

CAS 210880-92-5PubChem CID 86287519

Clothianidin

(E)-clothianidin is a clothiadin that has E configuration at the C=N bond of the nitroguanidine moiety. It has a role as a neonicotinoid insectide. — ChEBI

IUPAC name: 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine

Molecular formula: C6H8ClN5O2S
Molecular weight: 249.68 g/mol
Exact mass: 249.0087234 Da
XLogP3: 1.3
Topological polar surface area: 123.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

CeleroPonchoTI 435Poncho 600PanchoTI-4352V9906ABKQCGA-322704

16 more reported names

CHEBI:391781-((2-chloro-1,3-thiazol-5-yl)methyl)-3-methyl-2-nitroguanidineRefChem:577765433-460-11-((2-chloro-1,3-thiazol-5-yl)methyl)-2-methyl-3-nitroguanidine(E)-clothianidinClothianidin [ISO]CLOTHIANIDINE1-(2-chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidineCHEBI:39177(E)-1-((2-chlorothiazol-5-yl)methyl)-3-methyl-2-nitroguanidine(E)-N-(2-chloro-5-thiazolyl)methyl-N'-methyl-N''-nitroguanidine(E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidineGuanidine, N-((2-chloro-5-thiazolyl)methyl)-N'-methyl-N''-nitro-, (C(E))-Guanidine, N-(2-chloro-5-thiazolyl)methyl-N'-methyl-N''-nitro-, (E)-Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitro-, [C(E)]-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:39177
ChEMBL:CHEMBL259727
EPA DTXSID:DTXSID2034465
PubMed:42068652
PubMed:39800138
PubMed:39393466
PubMed:39151607
PubMed:39025286
PubMed:38311399
PubMed:36858607
PubMed:36084723
PubMed:35690182
PubMed:35264496
PubMed:33563863
PubMed:33426623

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 210880-92-5

1 total

Annex

Entry

1734

clothianidin (ISO); (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine

433-460-1

How CAS 210880-92-5 is used on this site

CAS 210880-92-5 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 210880-92-5 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 210880-92-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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