CAS 18684-24-7PubChem CID 11902893
Prolylhydroxyproline
Pro-Hyp is a dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation. It has a role as a diagnostic agent, a biomarker and a human metabolite. It is functionally related to a L-proline and a trans-4-hydroxy-L-proline. It is a tautomer of a Pro-Hyp zwitterion. — ChEBI
- IUPAC name
- (2S,4R)-4-hydroxy-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
- Molecular formula
- C10H16N2O4
- Molecular weight
- 228.24 g/mol
- Exact mass
- 228.11100700 Da
- XLogP3
- -3.3
- Topological polar surface area
- 89.9 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 3
Also known as
(2S,4R)-4-hydroxy-1-(((2S)-pyrrolidin-2-yl)carbonyl)pyrrolidine-2-carboxylic acid(2S,4R)-4-hydroxy-1-((2S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid(2S,4R)-4-hydroxy-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid(2S,4R)-4-hydroxy-1-((2S)-pyrrolidin-1-ium-2-carbonyl)pyrrolidine-2-carboxylate(2S,4R)-4-hydroxy-1-[(2S)-pyrrolidin-1-ium-2-carbonyl]pyrrolidine-2-carboxylateRefChem:1096641H-Pro-Hyp-OHPro-Hyp
16 more reported names
Pro-Hyp-OHL-Prolyl-L-hydroxyproline(2S,4R)-1-(L-prolyl)-4-hydroxypyrrolidine-2-carboxylic acid(2S,4R)-4-hydroxy-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid(2S,4R)-4-Hydroxy-1-[(2S)-2-pyrrolidinylcarbonyl]-2-pyrrolidinecarboxylic acid(2S,4R)-4-Hydroxy-1-[(S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic Acid4-Hydroxy-1-L-prolyl-proline; 4-Hydroxy-1-L-prolyl-L-proline; L-Prolyl-L-hydroxyproline; Prolylhydroxyprolineproline-hydroxyprolineL-Pro-L-HypL-Proline, L-prolyl-4-hydroxy-, (4R)-W8TTC0Y1XYG-30254-hydroxy-1-L-prolyl-Proline(2S,4R)-4-hydroxy-1-CHEBI:74767L-4-hydroxy-1-L-prolyl-Proline
External database identifiers
- ChEBI:CHEBI:74767
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.