CAS 157283-68-6 — 0 EU Cosmetic Records

Chemical identity and properties

PubChem 2D chemical structure for CAS 157283-68-6

CAS 157283-68-6PubChem CID 5282226

Travoprost

Travoprost is the isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the cornea to the biologically active free acid, fluprostenol. It has a role as an antihypertensive agent, an antiglaucoma drug, a prodrug, a prostaglandin receptor agonist and an ophthalmology drug. It is an isopropyl ester, a prostaglandins Falpha and a member of (trifluoromethyl)benzenes. It is functionally related to a fluprostenol. — ChEBI

IUPAC name: propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate

Molecular formula: C26H35F3O6
Molecular weight: 500.5 g/mol
Exact mass: 500.23857332 Da
XLogP3: 4.1
Topological polar surface area: 96.2 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 5

Also known as

TravatanTravatan ZIzbaAL-6221AL6221Otx-tptravoprostumIDOSE TR

16 more reported names

WJ68R08KX9CHEBI:746859NSC-760366DUOTRAV COMPONENT TRAVOPROSTpropan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl]cyclopentyl]hept-5-enoate5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl ester, (5Z)-isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(alpha,alpha,alpha-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoatepropan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoateZ, TravatanAL 6221ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((alpha,alpha,alpha-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATEpropan-2-yl (5Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoateTravoprost OphthalmicTravoprost IntracameralRefChem:56256Travoprost (Isomer Free)

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External database identifiers

ChEBI:CHEBI:746859
ChEMBL:CHEMBL1200799
EPA DTXSID:DTXSID80896948
PubMed:19929706
PubMed:19403113
PubMed:19038618
PubMed:18983226
PubMed:18837686
PubMed:18452763
PubMed:15321024
PubMed:9038626

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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