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CAS 1 record

CAS 1308-38-9

CAS 1308-38-9 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1308-38-9
CAS 1308-38-9PubChem CID 517277

Chromia

Dichromium trioxide is a chromium oxide. — ChEBI

IUPAC name
oxo(oxochromiooxy)chromium
Molecular formula
Cr2O3
Molecular weight
151.990 g/mol
Exact mass
151.865753 Da
Topological polar surface area
43.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Chromium(III) oxideDichromium trioxideCHROMIC OXIDEChrome oxideChrome GreenGreen chromium oxideGreen cinnabarChrome ochre
16 more reported names
Chromium Oxide GreenAnadonis GreenCasalis GreenGreen rougeChrome OcherLeaf greenChromium(3+) oxideLevanox green gachromium (III) oxideOxide of chromiumGreen oxide of chromiumGreen chrome oxideChromic Acid GreenGreen chromic oxideChrome Green F 3Chromium oxide (Cr2O3)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match517277

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 57.8% (1112 of 1924) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (24%): Harmful if swallowed [Warning Acute toxicity, oral]; H317 (25.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (24.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H360 (14.6%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P318, P321, P330, P333+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1924 reports by companies from 27 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1112 of 1924 reports by companies.; There are 23 notifications provided by 812 of 1924 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P233, P260, P261, P264, P270, P271, P272, P280, P284, P302+P352, P304+P340, P319, P321, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] Source: NITE-CMC
  • Precautionary Statement Codes: P233, P260, P261, P271, P272, P280, P284, P302+P352, P304+P340, P321, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Health Effects: Chromium in its trivalent state is not very toxic. It may be oxidized to hexavalent chromium, a known carcinogen. Hexavalent chromium has also been shown to affect reproduction and development. (A12) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: IDENTIFICATION AND USE: Chromic oxide (Cr(2)O(3)) is a green powder. It is not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. It is used in abrasives and electric semiconductors; in alloys; in printing fabrics and banknotes. It is also used in dyeing polymers; colorant for latex paints, in manufacturing of chromium metal and aluminum-chromium master alloys. It's other uses include catalyst in organic synthesis, green granules in asphalt roofing, component of refractory brick. Chromic oxide is a color additive in drug use. HUMAN EXPOSURE AND TOXICITY: Fine chromic oxide particles were insoluble in the culture medium; on the contrary, Cr(2)O(3) nanoparticles released soluble hexavalent chromium into the culture medium. Human lung carcinoma A549 cells and human keratinocyte HaCaT cells showed an increase in intracellular reactive oxygen species (ROS) level and activation of antioxidant defense systems on exposure to Cr(2)O(3) nanoparticles. The cellular influences of Cr(2)O(3) nanoparticles matched those of hexavalent chromium. Human lung epithelial c Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36) Source: Toxin and Toxin Target Database (T3DB)
  • Consumer Uses: Other; Processing aids not otherwise specified; Catalyst; Not Known or Reasonably Ascertainable; Corrosion inhibitor; Pigment Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used in abrasives, refractory materials, semiconductors, pigments, alloys, textile printing inks, and catalysts; [Merck Index] Used as a pigment in polymers and latex paints; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Semiconductor Manufacturing [Category: Industry]; Painting (Pigments, Binders, and Biocides) [Category: Paint]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For chromic oxide (USEPA/OPP Pesticide Code: 021103) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: In abrasives, refractory materials, electric semiconductors; as pigment, particularly in coloring glass; in alloys; in printing fabrics and banknotes; catalyst for organic and inorganic reactions. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Used in dyeing polymers, ... colorant for latex paints. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: In metallurgy in the manufacture of chromium metal and aluminum-chromium master alloys. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for Chromium (III) oxide (11 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Plastics -> Typical concentration range in plastic materials -> 1% Source: NORMAN Suspect List Exchange
  • Uses: Chromium(III) oxide is commonly used as pigment, under the name viridian, in paints, inks, and glasses. (L523) Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 1308-38-9

1 total

How CAS 1308-38-9 is used on this site

CAS 1308-38-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 1308-38-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 1308-38-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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