CAS 122-00-9PubChem CID 8500
p-METHYLACETOPHENONE
4'-Methylacetophenone is an aromatic ketone. — ChEBI
- IUPAC name
- 1-(4-methylphenyl)ethanone
- Molecular formula
- C9H10O
- Molecular weight
- 134.17 g/mol
- Exact mass
- 134.073164938 Da
- XLogP3
- 2.1
- Topological polar surface area
- 17.1 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
4'-MethylacetophenoneMelilotal4-METHYLACETOPHENONEp-Methyl acetophenoneEthanone, 1-(4-methylphenyl)-Acetophenone, 4'-methyl-1-(4-Methylphenyl)ethan-1-one4-Methylphenyl methyl ketone
16 more reported names
FEMA No. 2677AX66V0KX3YNSC-9401RefChem:858125204-514-81-(p-Tolyl)ethanone4-AcetyltolueneMethyl p-tolyl ketone1-p-Tolylethanonep-Acetotoluenep-Acetyltoluene1-Acetyl-4-methylbenzene1-Methyl-4-acetylbenzeneEsberivenpara-methyl acetophenone4'-METHYLACETO-D3-PHENONE
External database identifiers
- ChEBI:CHEBI:178626
- ChEMBL:CHEMBL271871
- EPA DTXSID:DTXSID9044374
- PubMed:22429095
- PubMed:22356462
- PubMed:21936552
- PubMed:21866703
- PubMed:21754040
- PubMed:21673897
- PubMed:21588669
- PubMed:21582553
- PubMed:21581305
- PubMed:21581097
- PubMed:21581092
- PubMed:21580694
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match8500
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 222.00 to 226.00 °C. @ 756.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 226 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 0.999-1.010 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- LogP: 2.10 Source: Human Metabolome Database (HMDB)
- Melting Point: 28 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Clear, light yellow liquid; mp = 22-24 deg C; [Sigma-Aldrich MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Physical Description: low melting colourless or opaque crystalline mass (tends to supercool) with a strong fruity-floral, warm, sweet odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: 1.530-1.536 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: 0.372 mg/mL at 15 °C Source: Human Metabolome Database (HMDB)
- Solubility: insoluble in water; soluble in organic solvents, oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: very soluble (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.22 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1848) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (83.3%): Causes skin irritation [Warning Skin corrosion/irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P321, P330, P332+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1848 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 1848 reports by companies.; There are 7 notifications provided by 1847 of 1848 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral] Source: NITE-CMC
- Precautionary Statement Codes: P210, P264, P270, P280, P301+P317, P330, P370+P378, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as flavoring agent or adjuvant; [FDA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.