CAS 120-08-1 — 0 EU Cosmetic Records

Chemical identity and properties

PubChem 2D chemical structure for CAS 120-08-1

CAS 120-08-1PubChem CID 8417

Scoparone

Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. It has a role as an antihypertensive agent, an antilipemic drug, an immunosuppressive agent, an anti-allergic agent, an anti-inflammatory agent and a plant metabolite. It is a member of coumarins and an aromatic ether. It is functionally related to an esculetin. — ChEBI

IUPAC name: 6,7-dimethoxychromen-2-one

Molecular formula: C11H10O4
Molecular weight: 206.19 g/mol
Exact mass: 206.05790880 Da
XLogP3: 1.9
Topological polar surface area: 44.8 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

6,7-DIMETHOXYCOUMARIN6,7-DimethylesculetinEscoparoneScoparon6,7-Dimethoxy-2H-chromen-2-oneEsculetin dimethyl etherAesculetin dimethyl etherScopoletin methyl ether

16 more reported names

o-Methylscopoletin6,7-Dimethoxy-2H-1-benzopyran-2-oneo-Methylisoscopoletino,o-Dimethylesculetin6,7-Dimethoxy-Coumarin6,7-Dimethoxybenzopyran-2-oneEsculetin 6,7-dimethyl etherH5841PDT4YCHEBI:9055RefChem:181956204-369-06,7-Dimethoxy-2-benzopyrone2H-1-Benzopyran-2-one, 6,7-dimethoxy-Dimethyl esculetinCoumarin, 6,7-dimethoxy-Benzopyran-2-one, 6,7-dimethoxy-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:9055
ChEMBL:CHEMBL325864
EPA DTXSID:DTXSID10152640
PubMed:37449671
PubMed:36542898
PubMed:28299617
PubMed:25315519
PubMed:24685503
PubMed:24333270
PubMed:24176340
PubMed:23535186
PubMed:23086487
PubMed:23017425
PubMed:22870812
PubMed:22654640

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match8417

Attributed physical-property, hazard, environmental and use annotations.

Melting Point: 144 °C Source: Human Metabolome Database (HMDB)

Physical Description: Solid Source: Human Metabolome Database (HMDB)

Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H319 (97.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P316, P305+P351+P338, P321, P330, P337+P317, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 42 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 120-08-1

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How CAS 120-08-1 is used on this site

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