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CAS 1 record

CAS 110102-85-7

CAS 110102-85-7 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 110102-85-7
CAS 110102-85-7PubChem CID 22153846

5-Amino-4-chloro-o-cresol hydrochloride

The Expert Panel for Cosmetic Ingredient Safety concluded that 5-Amino-4-Chloro-o-Cresol and 5-Amino-4-Chloro-o-Cresol HCl are safe for use as oxidative hair dye ingredients in the present practices of use and concentration described in this safety assessment. — Cosmetic Ingredient Review (CIR)

IUPAC name
5-amino-4-chloro-2-methylphenol;hydrochloride
Molecular formula
C7H9Cl2NO
Molecular weight
194.06 g/mol
Exact mass
193.0061193 Da
Topological polar surface area
46.3 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
2
Covalent units
2
Defined stereocentres
0

Also known as

5-AMINO-4-CHLORO-O-CRESOL HCLUNII-31J4UQW59L31J4UQW59LPhenol, 5-amino-4-chloro-2-methyl-, hydrochloride2-Methyl-4-chloro-5-aminophenol hydrochloride5-Amino-4-chloro-o-cresol HCl [INCI]Phenol, 5-amino-4-chloro-2-methyl-, hydrochloride (1:1)RefChem:101961
8 more reported names
5-amino-4-chloro-2-methylphenol hydrochlorideKPBXDJZVHWRFLV-UHFFFAOYSA-NDS-12389DB-3587582-methyl-4-chloro-5-aminophenolhydrochloride5-amino-4-chloro-2-methylphenolhydrochlorideCS-01628295-amino-4-chloro-2-methyl-phenol;hydrochloride
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match22153846

Attributed physical-property, hazard, environmental and use annotations.

  • Cosmetic Ingredient Review Conclusion: The Expert Panel for Cosmetic Ingredient Safety concluded that 5-Amino-4-Chloro-o-Cresol and 5-Amino-4-Chloro-o-Cresol HCl are safe for use as oxidative hair dye ingredients in the present practices of use and concentration described in this safety assessment. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 110102-85-7

1 total
Annex
III
Entry
208

5-Amino-4-Chloro-o-Cresol HCl

5-Amino-4-chloro-2-methylphenol hydrochloride

To be printed on the label: Hair colorants can cause severe allergic reactions.

EC
—

How CAS 110102-85-7 is used on this site

CAS 110102-85-7 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 110102-85-7 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 110102-85-7 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.
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