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CAS 1 record

CAS 107-30-2

CAS 107-30-2 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 107-30-2
CAS 107-30-2PubChem CID 7864

Chloromethyl Methyl Ether

Chloromethyl methyl ether is an ether. — ChEBI

IUPAC name
chloro(methoxy)methane
Molecular formula
C2H5ClO
Molecular weight
80.51 g/mol
Exact mass
80.0028925 Da
XLogP3
0.8
Topological polar surface area
9.2 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

Methane, chloromethoxy-Chlorodimethyl etherChloromethoxymethaneMethoxymethyl chlorideMethyl chloromethyl etherMethoxychloromethaneCMMEChlordimethylether
16 more reported names
DimethylchloroetherEther, chloromethyl methylEther, dimethyl chloroMonochlorodimethyl etherMethylchloromethyl etherMonochloromethyl methyl etherEther methylique monochloreRCRA waste number U046alpha,alpha-Dichlorodimethyl etherMethyl chloromethyl ether, anhydrous334G5B96VGNSC-21208chlorodimethyletherchloromethyl methyl methoxychloromethaneRefChem:125444203-480-1
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:82271

Chloromethyl methyl ether

Formula
C2H5ClO
Average mass
80.514 g/mol
Monoisotopic mass
80.00289 Da
Formal charge
0
  • ether — is a (CHEBI:25698)
  • ether — is a (CHEBI:25698)
Cross-references from this source
  • CAS: 107-30-2 — KEGG COMPOUND
  • MANUAL_X_REF: C19160 — KEGG COMPOUND
  • MANUAL_X_REF: HMDB0031332 — HMDB

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7864

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: Signs and Symptoms of Chloromethyl Methyl Ether Exposure: Acute exposure to chloromethyl methyl ether may produce severe irritation and burning of the skin, eyes, and mucous membranes. Sore throat, fever, chills, dypsnea (difficulty breathing), chronic bronchitis, and pulmonary edema with productive cough may be noted.; Emergency Life-Support Procedures: Acute exposure to chloromethyl methyl ether may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.; Inhalation Exposure:; 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to chloromethyl methyl ether.; 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.; 3. Obtain aut Source: CAMEO Chemicals
  • ERG2024, Guide 131 (Methyl chloromethyl ether): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Soap wash immediately - If this chemical contacts the skin, immediately wash the contaminated skin with soap and water. If this chemical penetrates the clothing, immediately remove the clothing, wash the skin with soap and water, and get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H332: Harmful if inhaled [Warning Acute toxicity, inhalation]; H350: May cause cancer [Danger Carcinogenicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P317, P318, P321, P330, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]; H302+H312+H332 (84.4%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]; H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H319 (84.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H350 (100%): May cause cancer [Danger Carcinogenicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P321, P330, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 45 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350: May cause cancer [Danger Carcinogenicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P320, P321, P330, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H301: Toxic if swallowed [Danger Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H350: May cause cancer [Danger Carcinogenicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P319, P320, P321, P330, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Toxicity Summary: ... Based upon the lack of persistence of BCME /bis(chloromethyl) ether/ and CMME /chloromethyl methyl ether/ in the environment, average human exposure to these compounds is likely to be very low. ... General population exposure to BCME and CMME occurs where they are produced by the widespread burning of this synergist in mosquito coils. ...Quantitative information on the kinetics and metabolism ... in humans is not available. However, it is anticipated that although in vivo BCME and CMME would be rapidly hydrolyzed in tissues to formaldehyde and hydrogen chloride, and methanol, formaldehyde and hydrogen chloride, respectively, there should be alkylation activity. ... BCME and CMME are acutely toxic by inhalation or ingestion. ...During inhalation of BCME /in laboratory animal studies/, irritation of the eyes and respiratory tract were noted as well as necrotizing bronchitis. Skin application resulted in erythema and necrosis, and application to the eye resulted in corneal necrosis. Similar effects were noted after exposure to CMME. Increased mortality and tracheal hyperplasia were observed in rats and hamsters following multiple inhalation exposure to ... BCME ... Similar results Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: Hydrolysis half-lives are sufficiently fast (hydrolysis occurs in pure water with a half-life <1 sec(1)) to preclude any possibility of bioconcentration in the food chain(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: The fate of chloromethyl methyl ether in moist soil is unknown. However, since it hydrolyzes so rapidly in pure water(1), it is expected to disappear rapidly from moist soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Chloromethyl methyl ether will hydrolyze instantaneously in water (half-life <1 sec)(1). Reaction products include methanol, formaldehyde, HCl, and chloromethylformate(1,2). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: Chloromethyl methyl ether will hydrolyze in humid air (half-life 3.5 min to 6.5 hr)(1,2). However, results suggest that the hydrolysis is surface catalyzed and therefore may not represent the true half-life in atmospheric room air or outside air(SRC). The half-life of chloromethyl methyl ether with photochemically-produced hydroxyl radicals has been determined to be approximately 7 days(3,SRC). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 107-30-2

1 total

How CAS 107-30-2 is used on this site

CAS 107-30-2 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 107-30-2 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

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A substance identified by CAS 107-30-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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