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CAS 1 record

CAS 10124-43-3

CAS 10124-43-3 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10124-43-3
CAS 10124-43-3PubChem CID 24965

Cobalt Sulfate

Cobalt(2+) sulfate is a compound of cobalt and sulfate in which the ratio of cobalt (+2 oxidation state) to sulfate is 1:1. It contains a cobalt(2+). — ChEBI

IUPAC name
cobalt(2+) sulfate
Molecular formula
CoO4S
Molecular weight
155.00 g/mol
Exact mass
154.884923 Da
Topological polar surface area
88.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Cobaltous sulfateCobalt(II) sulfateCobalt BrownCobalt monosulfateCobalt(II) sulphateCobalt (2+) sulfateCobalt sulfate (1:1)Cobalt(II) sulfate (1:1)
16 more reported names
Cobalt sulfate (CoSO4)Sulfuric acid, cobalt(2+) salt (1:1)Cobaltous sulfate salt (1:1)CoSO4H7965X29HXCOBALTOUS SULPHATECOBALT(2+) SULPHATECHEBI:53470COBALT SULPHATE (1:1)RefChem:127219Cobalt sulfate, 7-hydratelambda2-cobalt(2+) ion sulfateSulfuric Acid, Cobalt (2+) Salt (1:1) Heptahydrate233-334-2Cobalt sulphatecobalt(2+);sulfate
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:53470

cobalt(2+) sulfate

A compound of cobalt and sulfate in which the ratio of cobalt (+2 oxidation state) to sulfate is 1:1.

Formula
Co.O4S
Average mass
154.996 g/mol
Monoisotopic mass
154.88492 Da
Formal charge
0
  • metal sulfate — is a (CHEBI:51336)
  • cobalt(2+) — has part (CHEBI:48828)
  • metal sulfate — is a (CHEBI:51336)
Additional curated names
cobalt(2+) sulfateCobalt (2+) sulfateCobalt BrownCobalt(II) sulfateCobalt monosulfateCobaltous sulfateCobalt sulfateCoSO4
Cross-references from this source
  • CAS: 10026-24-1 — KEGG COMPOUND
  • CAS: 10124-43-3 — KEGG COMPOUND
  • CAS: 10124-43-3 — ChemIDplus
  • CAS: 10124-43-3 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 268815 — Gmelin
  • REGISTRY_NUMBER: 270126 — Gmelin
  • REGISTRY_NUMBER: 270959 — Gmelin
  • REGISTRY_NUMBER: 8292 — Gmelin
  • MANUAL_X_REF: C17383 — KEGG COMPOUND
  • MANUAL_X_REF: C19215 — KEGG COMPOUND

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2016-02-17. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match24965

Attributed physical-property, hazard, environmental and use annotations.

  • pH: Acidic salts, such as cobalt sulfate ... resulting aqueous solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. Source: Hazardous Substances Data Bank (HSDB)
  • First Aid: INHALATION: move to fresh air; if breathing has stopped, begin artificial respiration and call a doctor.; INGESTION: give large amount of water; induce vomiting; call a doctor.; EYES: flush with water for at least 15 min.; consult a physician if irritation persists.; SKIN: flush with water. (USCG, 1999) Source: CAMEO Chemicals
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350i: May cause cancer by inhalation [Danger Carcinogenicity]; H360F ***: May damage fertility [Danger Reproductive toxicity]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P318, P321, P330, P333+P317, P342+P316, P362+P364, P391, P403, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (99.8%): Harmful if swallowed [Warning Acute toxicity, oral]; H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (15.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H334 (> 99.9%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H341 (99.8%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350 (85.6%): May cause cancer [Danger Carcinogenicity]; H350i (14.4%): May cause cancer by inhalation [Danger Carcinogenicity]; H360 (84.1%): May damage fertility or the unborn child [Danger Reproductive toxicity]; H360F (10.5%): May damage fertility [Danger Reproductive toxicity]; H400 (99.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (97.3%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P233, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P321, P330, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2654 reports by companies from 34 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H350: May cause cancer [Danger Carcinogenicity] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] Source: NITE-CMC
  • Health Effects: Exposure to high amount of cobalt can cause heart, lung, kidney, and liver damage. Skin contact is known to result in contact dermatitis. Cobalt may also have mutagenic and carcinogenic effects. (L29, L30) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: IDENTIFICATION: Cobalt sulfate is a red powder. It is used in storage batteries; in cobalt-electroplating baths; as drier for lithographic inks, and varnishes; in ceramics, enamels, and glazes to prevent discoloring; in cobalt pigments for decorating porcelain. HUMAN EXPOSURE AND TOXICITY: Cardiomyopathy has been observed in individuals who consume large quantities of beer where cobalt sulfate was added as a foam stabilizer. Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma. The substance may have effects on the heart, thyroid and bone marrow, resulting in cardiomyopathy, goiter and polycythemia. ANIMAL STUDIES: Rats and mice exposed short term to cobalt sulfate by inhalation exhibited necrosis and inflammation of the respiratory tract epithelium. Rats developed thymus necrosis and testicular atrophy. Rats exposed for 2-3 months to cobalt sulfate in the diet for 24 weeks had significant reductions in heart enzyme activity levels. Rats and mice were exposed to cobalt sulfate heptahydrate by inhalation 6 hr/day, 5 days/week for 13 weeks developed adverse effects throughout the respiratory system. At higher concentra Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, causing increased lipid peroxidation, DNA damage, and inducing certain enzymes that lead to cell apoptosis. Cobalt has also been shown to block inorganic calcium channels, possibly impairing neurotransmission. Cobalt can also chelate lipoic acids, impairing oxidation of pyruvate or fatty acids. In addition, cobalt may inhibit DNA repair by interacting with zinc finger DNA repair proteins, and has also been shown to inhibit heme synthesis and glucose metabolism. Cobalt may activate specific helper T-lymphocyte cells and interact directly with immunologic proteins, such as antibodies (IgA and IgE) or Fc receptors, resulting in immunosensitization. (L29) Source: Toxin and Toxin Target Database (T3DB)
  • Environmental Bioconcentration: Food Chain Concentration Potential of Cobaltous Sulfate (heptahydrate): Bioconcentration of 200-1000 fold only under constant exposure. Not significant in spill conditions(1). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: Inorganic cobalt compounds are nonvolatile and released into the atmosphere in particulate form(1). Particulate-phase cobalt compounds are removed from the air by wet and dry deposition(SRC). Cobalt has been detected in atmospheric deposition(2) and in rain-snow precipitation(3). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Processing aids not otherwise specified; Plating agent; Intermediate; Pigment; Catalyst; Soil amendments (fertilizers) Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 10124-43-3

1 total

How CAS 10124-43-3 is used on this site

CAS 10124-43-3 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 10124-43-3 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

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A substance identified by CAS 10124-43-3 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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