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CAS 2 records

CAS 100-51-6

CAS 100-51-6 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 100-51-6
CAS 100-51-6PubChem CID 244

Benzyl Alcohol

Benzyl alcohol is an aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. It has a role as an antioxidant, a metabolite, a solvent and a fragrance. — ChEBI

IUPAC name
phenylmethanol
Molecular formula
C7H8O
Molecular weight
108.14 g/mol
Exact mass
108.057514874 Da
XLogP3
1.1
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

benzenemethanolphenylcarbinolBenzenecarbinolHydroxytolueneBenzoyl alcoholalpha-ToluenolPhenylmethyl alcohol(Hydroxymethyl)benzene
16 more reported names
Phenolcarbinolalpha-hydroxytolueneAlcool benzyliqueBenzal alcoholMethanol, phenyl-benzylic alcoholBenzylicumhydroxymethylbenzenePhenylcarbinolumUlesfiaAlcohol, BenzylAlcohol bencilicoalcoholum benzylicumFEMA No. 2137NCI-C06111Alcool benzilico
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:17987

benzyl alcohol

An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.

Formula
C7H8O
Average mass
108.140 g/mol
Monoisotopic mass
108.05751 Da
Formal charge
0
  • benzyl alcohols — is a (CHEBI:22743)
  • solvent — has role (CHEBI:46787)
  • metabolite — has role (CHEBI:25212)
  • antioxidant — has role (CHEBI:22586)
  • fragrance — has role (CHEBI:48318)
  • antiparasitic agent — has role (CHEBI:35442)
  • solvent — has role (CHEBI:46787)
  • metabolite — has role (CHEBI:25212)
  • antioxidant — has role (CHEBI:22586)
  • fragrance — has role (CHEBI:48318)
  • antiparasitic agent — has role (CHEBI:35442)
  • benzyl alcohols — is a (CHEBI:22743)
Additional curated names
phenylmethanolAlcohol, benzylAlcohol,benzylAlcohol benzylicusalcoholum benzylicumalcool benzyliquealpha-HydroxytolueneAromatic alcoholbenzenecarbinolBenzenemethanolBenzyl alcoholBenzylalkoholbenzylic alcoholE-1519E1519FEMA NO. 2137(hydroxymethyl)benzeneHydroxymethylbenzeneINS-1519INS NO.1519NSC-8044PhenylcarbinolPhenylmethanolphenylmethyl alcoholalpha-toluenol
Cross-references from this source
  • CAS: 100-51-6 — ChemIDplus
  • CAS: 100-51-6 — KEGG COMPOUND
  • CAS: 100-51-6 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 26514 — Gmelin
  • REGISTRY_NUMBER: 878307 — Reaxys
  • MANUAL_X_REF: 334 — DrugCentral
  • MANUAL_X_REF: Benzyl_Alcohol — Wikipedia
  • MANUAL_X_REF: BENZYL-ALCOHOL — MetaCyc
  • MANUAL_X_REF: C00029811 — KNApSAcK
  • MANUAL_X_REF: C00556 — KEGG COMPOUND
  • MANUAL_X_REF: c0278 — UM-BBD
  • MANUAL_X_REF: C03485 — KEGG COMPOUND
  • MANUAL_X_REF: D00077 — KEGG DRUG
  • MANUAL_X_REF: HMDB0003119 — HMDB

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2021-09-27. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match244

Attributed physical-property, hazard, environmental and use annotations.

  • Substance: Benzyl Alcohol Source: NTP Technical Reports
  • NTP Technical Report: TR-343: Toxicology and Carcinogenesis Studies of Benzyl Alcohol (CASRN 100-51-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (1989 ) Source: NTP Technical Reports
  • Peer Review Date: 11/06/87 Source: NTP Technical Reports
  • Conclusion for Male Rat: No Evidence Source: NTP Technical Reports
  • Conclusion for Female Rat: No Evidence Source: NTP Technical Reports
  • Conclusion for Male Mice: No Evidence Source: NTP Technical Reports
  • Conclusion for Female Mice: No Evidence Source: NTP Technical Reports
  • Summary: Under the conditions of these 2-year gavage studies, there was no evidence of carcinogenic activity of benzyl alcohol for male or female F344/N rats dosed with 200 or 400 mg/kg. Survival in both dose groups of female rats was 50% that of vehicle controls, primarily due to an increased number of gavage-related deaths. There was no evidence of carcinogenic activity of benzyl alcohol for male or female B6C3F1 mice dosed with 100 or 200 mg/kg for 2 years. Source: NTP Technical Reports
  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whene Source: CAMEO Chemicals
  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 4746) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (18.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (95.3%): Harmful if inhaled [Warning Acute toxicity, inhalation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P351+P338, P317, P330, P337+P317, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 4746 reports by companies from 43 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 4746 reports by companies.; There are 42 notifications provided by 4745 of 4746 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION: Benzyl alcohol is an aromatic organic alcohol, water-white in color with a faint aromatic odor and a sharp burning taste; it is a preservative, a solvent, and a local anesthetic. It is used in a wide variety of products including photographic developer for color movie films; dyeing nylon filament, textiles, and sheet plastics; solvent for dyestuffs, cellulose esters, casein, waxes; heat-sealing polyethylene films; intermediate for benzyl esters and ethers; bacteriostatic; cosmetics, ointments, emulsions; ball point pen inks; stencil inks. HUMAN EXPOSURE AND TOXICITY: Benzyl alcohol has been found to be irritating to the skin at levels 3% or greater. Patch test with 0.65% benzyl alcohol did not produce irritation of the skin. Benzyl alcohol poisoning can cause the gasping syndrome in neonates. The infants had a typical course of gradual neurologic deterioration, severe metabolic acidosis, the striking onset of gasping respirations, thrombocytopenia, hepatic and renal failure, hypotension, cardiovascular collapse and death. In every infant, unmetabolized benzyl alcohol was identified in the urine. Hypersensitivity reactions may occur after parenteral or dermal exposur Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 1.4 was calculated in fish for benzyl alcohol(SRC), using a log Kow of 1.10(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of <5(2) and 29(3) indicate that benzyl alcohol is expected to have very high mobility in soil(SRC). Volatilization of benzyl alcohol from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.37X10-7 atm-cu m/mole(4). Benzyl alcohol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 9.4X10-2 mm Hg at 25 °C(5). Utilizing the Japanese MITI test, 94% of the Theoretical BOD was reached in 2 weeks(6) indicating that biodegradation is an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values of <5(2) and 27(3) indicate that benzyl alcohol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected to be an important fate process(4) based upon a Henry's Law constant of 3.37X10-7 atm-cu m/mole(5). According to a classification scheme(6), an estimated BCF of 1.4(SRC), from its log Kow of 1.10(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Utilizing the Japanese MITI test, 94% of the Theoretical BOD was reached in 2 weeks(9) indicating that biodegradation is an important environmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), benzyl alcohol, which has a vapor pressure of 9.4X10-2 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor phase benzyl alcohol is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 2 days(SRC), calculated from its rate constant of 2.3X10-11 cu cm/molecule sec at 25 °C(3). Benzyl alcohol does not contain chromophores that absorb at wavelengths >290 nm(4) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Other; Solvent; Solvents (which become part of product formulation or mixture); Insulators; Preservative; Not Known or Reasonably Ascertainable; Fragrance; Cleaning agent Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Processing aids not otherwise specified; Flavoring and nutrient; Solvents (which become part of product formulation or mixture); Dispersing agent; Solvent; Foamant; Other; Intermediate; Solvents (for cleaning or degreasing); Hardener; Cleaning agent; Fragrance; Not Known or Reasonably Ascertainable; Filler; Preservative Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Benzyl Alcohol Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used as a preservative, epoxy resin catalyst, and in the photographic developer C-22; [Kanerva, p. 1757] Used as a preservative, solvent, and local anesthetic; [Marks, p. 136] Used as a preservative in drugs for injection; [Kanerva, p. 462-3] Used in flavors and perfumes and as a solvent for inks and dyes; [AIHA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean]; Plastic Composites Manufacturing [Category: Industry]; Photographic Processing [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For benzyl alcohol (USEPA/OPP Pesticide Code: 9502) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The active ingredient is no longer contained in any registered /pesticide/ products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
  • Uses: ... Photographic developer for color movie films; dyeing nylon filament, textiles, and sheet plastics; solvent for dyestuffs, cellulose esters, casein, waxes, etc.; heat-sealing polyethylene films; intermediate for benzyl esters and ethers; bacteriostat; cosmetics, ointments, emulsions; ball point pen inks; stencil inks. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Benzyl alcohol is used in cosmetics as a fragrance component, preservative, solvent, and viscosity-decreasing agent. In January 1998, benzyl alcohol was reported to be used in 322 cosmetic formulations. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for BENZYL ALCOHOL (13 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 100-51-6

2 total
Annex
III
Entry
45

BENZYL ALCOHOL

Benzyl Alcohol

For purposes other than inhibiting the development of microorganisms in the product. This purpose has to be apparent from the presentation of the product. The presence of the substance shall be indicated in the list of …

EC
202-859-9

How CAS 100-51-6 is used on this site

CAS 100-51-6 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 100-51-6 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

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A substance identified by CAS 100-51-6 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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