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Annex IV Entry 45 14/08/2020

N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

CI 20040

N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] appears in Annex IV as a positive-list colorant entry for EU cosmetics. Maximum concentration in this record: Rinse-off products.

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Permitted colorant— Annex IV, EU Regulation 1223/2009
Max conc.: Rinse-off products
Entry: 45

Chemical identity and properties

PubChem 2D chemical structure for CAS 5979-28-2
CAS 5979-28-2PubChem CID 22288

Pigment Yellow 16

IUPAC name
2-[(2,4-dichlorophenyl)diazenyl]-N-[4-[4-[[2-[(2,4-dichlorophenyl)diazenyl]-3-oxobutanoyl]amino]-3-methylphenyl]-2-methylphenyl]-3-oxobutanamide
Molecular formula
C34H28Cl4N6O4
Molecular weight
726.4 g/mol
Exact mass
726.089664 Da
XLogP3
10.0
Topological polar surface area
142.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
8
Covalent units
1
Defined stereocentres
0

Also known as

Light Yellow JNPV-Yellow GSiloton Yellow NCGChromatex Yellow JNPlastol Yellow 3GLHostaperm Yellow NCGHelio Fast Yellow FPVIrgalite Fast Yellow GC
16 more reported names
Segnale Light Yellow NCGPermanent Yellow NCGResamine Fast Yellow 3GLTermosolido Yellow GL SupraC.I. 20040CI 20040EINECS 227-783-3NSC 521238R3896P1A0HNSC-521238PERMANENT YELLOW NCG 70Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxo-Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-(2-(2,4-dichlorophenyl)diazenyl)-3-oxo-N,N'-(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxobutyramide)N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]Butanamide, N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxo-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

Rinse-off products

Warnings

Maximum 3,3'-dimethylbenzidine concentration in the colouring agent: 5 ppm

Colour index or glossary

CI 20040

Chemical name

N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

Chemical / IUPAC name

N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

Color

Yellow

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Identified ingredients

Key data

CAS
5979-28-2
EC
227-783-3
Annex
IV
Entry number
45

Inventory links for N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

Inventory Restriction reference
Ref 32738

CI 20040

CAS: 5979-28-2
EC: 227-783-3

Direct matches are limited for this record, so nearby entries from Annex IV are shown as well.

Annex IV 44
Nearby record in the same annex

CI 19140

CAS: 12225-21-7; 1934-21-0
EC: 235-428-9; 217-699-5
Annex IV 46
Nearby record in the same annex

CI 20470

CAS: 1064-48-8
EC: 213-903-1
Annex IV 43
Nearby record in the same annex

CI 18965

CAS: 6359-98-4
EC: 228-819-0
Annex IV 47
Nearby record in the same annex

CI 21100

CAS: 5102-83-0
EC: 225-822-9
Annex IV 42
Nearby record in the same annex

CI 18820

CAS: 6359-82-6
EC: 228-808-0
Annex IV 48
Nearby record in the same annex

CI 21108

CAS: 5567-15-7
EC: 226-939-8
Annex IV 41
Nearby record in the same annex

CI 18736

CAS: 6408-26-0
EC: 229-051-9
Annex IV 40
Nearby record in the same annex

CI 18690

CAS: 5601-29-6
EC: 227-022-5
Annex IV 50
Nearby record in the same annex

CI 24790

CAS: 13421-53-9
EC: 236-531-1
Annex IV 39
Nearby record in the same annex

CI 18130

CAS: 10236-37-0

What Annex IV means for N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] is an approved colorant listed in Annex IV of EU Cosmetics Regulation 1223/2009. Only colorants on this positive list may be used to colour cosmetic products on the EU market.

Some colorants in Annex IV are restricted by product type — for example, prohibited from use around the eyes or in products applied to mucous membranes. Check the product type and conditions fields above before use.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm colorant is used only in permitted product types listed above.
  • Record the Colour Index number and CAS identifier in the ingredient declaration.

Frequently asked questions

Yes. N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] is included in Annex IV of EU Cosmetics Regulation 1223/2009 as a permitted colorant. Only colorants on this positive list may be used to colour cosmetic products in the EU. Check the product type conditions above for any use restrictions.

CAS 5979-28-2 is the unique numerical identifier assigned to N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of Rinse-off products applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex IV record N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]

This page summarizes one Annex IV record for N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex IV conditions for N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide], but confirm any final regulatory decision against the current official annex wording and source files.

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