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Annex IV Entry 111 14/08/2020

CI Food Orange 5

CI 75130

CI Food Orange 5 appears in Annex IV as a positive-list colorant entry for EU cosmetics.

Search similar Back to annex Compare
Permitted colorant— Annex IV, EU Regulation 1223/2009
Entry: 111

Chemical identity and properties

PubChem 2D chemical structure for CAS 116-32-5
CAS 116-32-5CAS 7235-40-7PubChem CID 5280489

Beta-Carotene

Beta-Carotene is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04) — NCI Thesaurus (NCIt)

IUPAC name
1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene
Molecular formula
C40H56
Molecular weight
536.9 g/mol
Exact mass
536.438201786 Da
XLogP3
13.5
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

7235-40-7beta CaroteneBetacarotenebeta,beta-CaroteneSolateneCarotabenProvateneall-trans-beta-Carotene
16 more reported names
SerlaboFood orange 5BetaVitKPMKProvatenolLucaratinNatural Yellow 26Solatene (caps)BetacarotenoBetacarotenumKarotinbeta-KarotinC.I. Food Orange 5Zlut prirodni 26Beta, beta-caroteneCI Food Orange 5
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match5280489

Attributed physical-property, hazard, environmental and use annotations.

  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 311 of 368 companies Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 368 reports by companies from 7 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 311 of 368 reports by companies.; There are 6 notifications provided by 57 of 368 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Warnings

Purity criteria as set out in Commission Directive 95/45/EC (E 160a)

Colour index or glossary

CI 75130

Chemical name

CI Food Orange 5

Chemical / IUPAC name

CI Food Orange 5

Color

Orange

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Identified ingredients

Key data

CAS
116-32-5; 31797-85-0; 7235-40-7; -
EC
-; -; 230-636-6; 214-171-6
Annex
IV
Entry number
111

Inventory links for CI Food Orange 5

Inventory Restriction reference
Ref 32173

BETA-CAROTENE

CAS: 7235-40-7
EC: 230-636-6
Inventory Shared CAS number
Ref 32748

CI 40800

CAS: 116-32-5 / 7235-40-7 / 31797-85-0
EC: - 230-636-6 / -
Inventory Shared EC number
Ref 32749

CI 40820

CAS: 1962-15-8
EC: 214-171-6
Inventory Restriction reference
Ref 32805

CI 75130

CAS: 7235-40-7
EC: 230-636-6

Direct matches are limited for this record, so nearby entries from Annex IV are shown as well.

Annex IV 55
Shared CAS number

CI 40800

CAS: 116-32-5; 31797-85-0; 7235-40-7
EC: 230-636-6
Annex IV 56
Shared EC number

CI 40820

CAS: 1962-15-8
EC: 214-171-6
Annex IV 110
Nearby record in the same annex

CI 75125

CAS: 502-65-8
Annex IV 112
Nearby record in the same annex

CI 75135

CAS: 3763-55-1
Annex IV 109
Nearby record in the same annex

CI 75120

CAS: 1393-63-1; 542-40-5; 6983-79-5
EC: 215-735-4; 208-810-8; 230-248-7
Annex IV 113
Nearby record in the same annex

CI 75170

CAS: 73-40-5
EC: 200-799-8
Annex IV 108
Nearby record in the same annex

CI 75100

CAS: 27876-94-4; 89382-88-7
EC: 248-708-0;
Annex IV 114
Nearby record in the same annex

CI 75300

CAS: 458-37-7; 94875-80-6
EC: 207-280-5; -
Annex IV 107
Nearby record in the same annex

CI 74260

CAS: 1328-53-6
EC: 215-524-7
Annex IV 115
Nearby record in the same annex

CI 75470

CAS: 1260-17-9; 1343-78-8; -
EC: 215-724-4; 215-680-6; 215-023-3
Annex IV 106
Nearby record in the same annex

CI 74180

CAS: 1330-38-7
EC: 215-537-8
Annex IV 116
Nearby record in the same annex

CI 75810

CAS: 11006-34-1; 8049-84-1
EC: 234-242-5; 232-471-5 ; 215-800-7 / 207-536-6 / 208-272-4 / 287-483-3 / 239-830-5 / 246-020-5

What Annex IV means for CI Food Orange 5

CI Food Orange 5 is an approved colorant listed in Annex IV of EU Cosmetics Regulation 1223/2009. Only colorants on this positive list may be used to colour cosmetic products on the EU market.

Some colorants in Annex IV are restricted by product type — for example, prohibited from use around the eyes or in products applied to mucous membranes. Check the product type and conditions fields above before use.

This record is linked to 4 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm colorant is used only in permitted product types listed above.
  • Record the Colour Index number and CAS identifier in the ingredient declaration.

Frequently asked questions

Yes. CI Food Orange 5 is included in Annex IV of EU Cosmetics Regulation 1223/2009 as a permitted colorant. Only colorants on this positive list may be used to colour cosmetic products in the EU. Check the product type conditions above for any use restrictions.

CAS 116-32-5; 31797-85-0; 7235-40-7; - is the unique numerical identifier assigned to CI Food Orange 5 by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex IV record CI Food Orange 5

This page summarizes one Annex IV record for CI Food Orange 5 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex IV conditions for CI Food Orange 5, but confirm any final regulatory decision against the current official annex wording and source files.

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