Annex III Source last update: 02/03/2026

Restricted cosmetic substances

LIST OF SUBSTANCES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO THE RESTRICTIONS LAID DOWN

Records on this page set

373

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Use these pages for research, discovery and comparison, but verify critical regulatory decisions against the official source text and current law.

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Records

373 total

Entry

377

Alpha-Arbutin

4-Hydroxyphenyl-alpha-D-glucopyranoside

Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance an…

CAS

84380-01-8

617-561-8

Max concentration Product type 04/04/2024

Entry

378

Arbutin

4-Hydroxyphenyl-beta-D-glucopyranoside

CAS

497-76-7

207-850-3

Max concentration Product type 04/04/2024

Entry

379

Silver

Silver (powder) [100 nm < particle diameter < 1 mm]

(a) Toothpaste (b) Mouthwash

CAS

7440-22-4

231-131-3

Max concentration Product type 15/01/2026

Entry

N,N',N'-Tris(polyoxyethylene)-N-hexadecylpropylenediamine dihydrofluoride

Contains N,N',N'-tris(polyoxyethylene)-N-hexadecylpropylenediamine dihydrofluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled …

CAS

—

Max concentration Product type 14/05/2013

Entry

380

Hexyl Salicylate

Hexyl 2-hydroxybenzoate

Not to be used in preparations for children under 3 years of age, with the exception of (d) “Toothpaste” and (f).

CAS

6259-76-3

228-408-6

Max concentration Product type 15/01/2026

Entry

OCTADECENYLAMMONIUM FLUORIDE

Octadecenyl- Ammonium Fluoride

Contains octadecenyl-ammonium fluoride. For any toothpaste with compounds containing fluorine in a concentration of 0,1 to 0,15 % calculated as F unless it is already labelled as contra-indicated for children (e.g. “for…

CAS

36505-83-6

—

Max concentration Product type 05/07/2023

Entry

AMMONIA

Ammonia

Above 2%: Contains ammonia

CAS

7664-41-7 / 1336-21-6

231-635-3 / 215-647-6

Max concentration 17/10/2010

Entry

SODIUM FLUOROSILICATE

Sodium Fluorosilicate

Contains sodium fluorosilicate For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult us…

CAS

16893-85-9

240-934-8

Max concentration Product type 14/05/2013

Entry

POTASSIUM FLUOROSILICATE

Potassium Fluorosilicate

Contains potassium fluorosilicate For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult…

CAS

16871-90-2

240-896-2

Max concentration Product type 14/05/2013

Entry

Ammonium fluorosilicate

Contains ammonium fluorosilicate For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult …

CAS

16919-19-0

240-968-3

Max concentration Product type 14/05/2013

Entry

MAGNESIUM FLUOROSILICATE

Magnesium Fluorosilicate

Contains magnesium fluorosilicate For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult…

CAS

16949-65-8

241-022-2

Max concentration Product type 14/05/2013

Entry

DIMETHYLOL ETHYLENE THIOUREA

1,3-Bis(hydroxymethyl)imidazolidine-2-thione

Contains Dimethylol ethylene thiourea

CAS

15534-95-9

239-579-1

Max concentration Product type 17/10/2010

Entry

BENZYL ALCOHOL

Benzyl Alcohol

For purposes other than inhibiting the development of microorganisms in the product. This purpose has to be apparent from the presentation of the product. The presence of the substance shall be indicated in the list of …

CAS

100-51-6

202-859-9

Product type 03/10/2023

Entry

6-Methylcoumarin

The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products

CAS

92-48-8

202-158-8

Max concentration Product type 11/09/2023

Entry

NICOMETHANOL HYDROFLUORIDE

Nicomethanol Hydrofluoride

Contains nicomethanol hydrofluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adu…

CAS

62756-44-9

—

Max concentration Product type 14/05/2013

Entry

SILVER NITRATE

Silver nitrate

Contains silver nitrate Rinse eyes immediately if product comes into contact with them

CAS

7761-88-8

231-853-9

Max concentration Product type 17/10/2010

Entry

Selenium disulphide

Selenium sulfide

Contains selenium disulphide Avoid contact with eyes or damaged skin

CAS

7488-56-4

231-303-8

Max concentration Product type 17/10/2010

Entry

Chloramine-T

Tosylchloramide sodium (INN)

CAS

127-65-1

204-854-7

Max concentration 17/10/2010

Entry

Aluminium zirconium chloride hydroxide complexes AlxZr(OH)yClz and the aluminium zirconium chloride hydroxide glycine complexes

Do not apply to irritated or damaged skin

CAS

—

Max concentration Product type 17/10/2010

Entry

OXYQUINOLINE SULFATE

bis(8-hydroxyquinolinium) sulphate

(a) Stabilizer for hydrogen peroxide in rinse-off hair products (b) Stabilizer for hydrogen peroxide in leave-on hair products

CAS

134-31-6

205-137-1

Max concentration Product type 31/07/2020

Entry

METHYL ALCOHOL

Methanol

Denaturant for ethanol and isopropyl alcohol

CAS

67-56-1

200-659-6

Max concentration Product type 17/10/2010

Entry

Etidronic acid

(1-Hydroxyethylidene)diphosphonic acid and its salts

(a) Hair product (b) Soap

CAS

2809-21-4

220-552-8

Max concentration Product type 17/10/2010

Entry

1-Phenoxypropan-2-ol (8)

For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product

CAS

770-35-4

212-222-7

Max concentration Product type 09/11/2010

Entry

MAGNESIUM FLUORIDE

Magnesium fluoride

Contains magnesium fluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult use o…

CAS

7783-40-6

231-995-1

Max concentration Product type 14/05/2013

Entry

STRONTIUM CHLORIDE

Strontium chloride hexahydrate

Contains strontium chloride Frequent use by children is not advisable

CAS

10476-85-4

233-971-6

Max concentration Product type 17/10/2010

Entry

STRONTIUM ACETATE

Strontium acetate hemihydrate

Contains strontium acetate Frequent use by children is not advisable

CAS

543-94-2

208-854-8

Max concentration Product type 17/10/2010

Entry

TALC

Talc: Hydrated magnesium silicate

(a) Keep powder away from children's nose and mouth

CAS

14807-96-6

238-877-9

Product type 22/10/2024

Entry

POTASSIUM CHLORATE / SODIUM CHLORATE

Chlorates of alkali metals

(a) Toothpaste (b) Other products

CAS

3811-04-9 / 7775-09-9

223-289-7 / 231-887-4

Max concentration Product type 04/11/2010

Entry

Fatty acid dialkylamides and dialkanolamides

- Do not use with nitrosating systems - Maximum secondary amine content: 5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

CAS

—

Max concentration 20/01/2023

Entry

Monoalkylamines, monoalkanolamines and their salts

- Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

CAS

—

Max concentration 18/06/2019

Entry

Trialkylamines, trialkanolamines and their salts

(a) (b) - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

CAS

—

Max concentration Product type 17/10/2010

Entry

STRONTIUM HYDROXIDE

Strontium hydroxide

Keep out of reach of children Avoid contact with the eyes

CAS

18480-07-4

242-367-1

Max concentration Product type 17/10/2010

Entry

Strontium peroxide

Avoid contact with eyes Rinse eyes immediately if product comes into contact with them For professional use only Wear suitable gloves

CAS

1314-18-7

215-224-6

Max concentration Product type 17/10/2010

Entry

BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

Benzalkonium chloride, bromide and saccharinate (9)

Avoid contact with the eyes

CAS

91080-29-4 / 63449-41-2 / 68391-01-5 / 68424-85-1 / 85409-22-9 / 68989-01-5

293-522-5 / 264-151-6 / 269-919-4 / 270-325-2 / 287-089-1 / 273-545-7

Max concentration Product type 04/11/2010

Entry

Polyacrylamides

(a) Maximum residual acrylamide content 0.1mg/kg (b) Maximum residual acrylamide content 0.5mg/kg

CAS

—

Product type 17/10/2010

Entry

Amyl cinnamal

2-Benzylideneheptanal

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

122-40-7

204-541-5

17/10/2010

Entry

Cinnamyl alcohol

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

104-54-1

203-212-3

17/10/2010

Entry

Citral; Geranial; Neral

3,7-Dimethyl-2,6-octadienal; (E)-3,7-dimethylocta-2,6-dienal; (Z)-3,7-dimethylocta-2,6-dienal

The presence of the substance or substances shall be indicated as ‘Citral’ in the list of ingredients referred to in Article 19(1), point (g), when the concentration of the substance or substances exceeds: — 0,001 % in …

CAS

5392-40-5; 141-27-5; 106-26-3

226-394-6; 205-476-5; 203-379-2

11/09/2023

Entry

Eugenol

Phenol, 2-methoxy-4-(2-propenyl)-

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

97-53-0

202-589-1

17/10/2010

Entry

HYDROXYCITRONELLAL

Hydroxycitronellal

(a) (b) The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)(g) when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products

CAS

107-75-5

203-518-7

Max concentration Product type 14/05/2013

Entry

ISOEUGENOL

Phenol, 2-methoxy-4-(1-propenyl); (E)-2-methoxy-4-(prop-1-enyl)phenol;(trans-Isoeugenol); (Z)-2-methoxy-4-(prop-1-enyl)phenol;(cis-Isoeugenol)

(a) (b) The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

CAS

97-54-1; 5932-68-3; 5912-86-7

202-590-7; 227-678-2; 227-633-7

Max concentration Product type 11/09/2023

Entry

Amylcinnamyl alcohol

2-Pentyl-3-phenylprop-2-en-1-ol

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

101-85-9

202-982-8

17/10/2010

Entry

Benzyl salicylate

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

118-58-1

204-262-9

02/08/2024

Entry

Cinnamal

2-Propenal, 3-phenyl-

The presence of the substance must be indicated in the list of ingredients referred to in Article 6(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

104-55-2

203-213-9

17/10/2010

Entry

Coumarin

2H-1-Benzopyran-2-one

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

91-64-5

202-086-7

17/10/2010

Entry

Geraniol

2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

106-24-1

203-377-1

17/10/2010

Entry

N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-Phenylenediamine (1 ), with exception of those derivatives li…

(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘blac…

CAS

—

Max concentration Product type 17/06/2014

Entry

ANISe ALCOHOL

4-Methoxybenzyl alcohol

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

105-13-5

203-273-6

04/11/2010

Entry

Benzyl cinnamate

2-Propenoic acid, 3-phenyl-, phenylmethyl ester

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

103-41-3

203-109-3

17/10/2010

Entry

Farnesol

2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-

The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

CAS

4602-84-0

225-004-1

17/10/2010

About this annex

Annex III covers substances that cosmetic products must not contain except under specific restrictions. These records often include warnings, conditions of use and concentration limits.

This section is especially useful for reviewing restricted substances, warning labels and product-type specific usage notes.