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Annex II Entry 334 CMR09/01/2011

Vinyl chloride monomer

Vinyl chloride monomer is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 334
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 75-01-4
CAS 75-01-4PubChem CID 6338

Vinyl Chloride

Chloroethene is a monohaloethene that is ethene in which one of the hydrogens has been replaced by a chloro group. It has a role as a carcinogenic agent. It is a gas molecular entity, a member of chloroethenes and a monohaloethene. — ChEBI

IUPAC name
chloroethene
Molecular formula
C2H3Cl
Molecular weight
62.50 g/mol
Exact mass
61.9923278 Da
XLogP3
1.5
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

ChloroethyleneEthene, chloro-MonochloroethyleneMonochloroetheneVinylchlorideEthylene monochlorideChlorethyleneVinylchlorid
16 more reported names
Monovinyl chlorideVinyl chloride monomerChloretheneChlorure de vinyleEthylene, chloro-TrovidurVinyl C monomerVinyl chlorineWinylu chlorekCloruro di vinileVinyle(chlorure de)RCRA waste number U043Vinile (cloruro di)1-ChloroethyleneWD06X94M2DCHEBI:28509
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Vinyl chloride monomer

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Other directives

(EC) 2009/552 - Shall not be used as propellant in aerosols for any use. Aerosols dispenser containing the substance as propellant shall not be placed on the market,(EC) 2008/1272

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1A✓——

Key data

CAS
75-01-4
EC
200-831-0
Annex
II
Entry number
334

Inventory links for Vinyl chloride monomer

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 328
Nearby record in the same annex

Tretamine (INN)

CAS: 51-18-3
EC: 200-083-5

What Annex II means for Vinyl chloride monomer

Vinyl chloride monomer is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Vinyl chloride monomer is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 75-01-4 is the unique numerical identifier assigned to Vinyl chloride monomer by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Vinyl chloride monomer has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Vinyl chloride monomer

This page summarizes one Annex II record for Vinyl chloride monomer from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Vinyl chloride monomer, but confirm any final regulatory decision against the current official annex wording and source files.

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