Furazolidone (INN)
Furazolidone (INN) is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.
Chemical identity and properties
Furazolidone
Furazolidone is a member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. It has a role as an antiinfective agent, an antibacterial drug, an EC 1.4.3.4 (monoamine oxidase) inhibitor and an antitrichomonal drug. It is a member of oxazolidines and a nitrofuran antibiotic. — ChEBI
- IUPAC name
- 3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
- Molecular formula
- C8H7N3O5
- Molecular weight
- 225.16 g/mol
- Exact mass
- 225.03857033 Da
- XLogP3
- -0.1
- Topological polar surface area
- 101.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Chemical name
Furazolidone (INN)
Chemical / IUPAC name
2-Oxazolidinone, 3-((5-nitrofurfurylidene)amino)-
Regulatory information
Key data
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What Annex II means for Furazolidone (INN)
Furazolidone (INN) is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.
Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.
The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Verify this substance is absent from all raw materials and finished formulations.
- Request absence confirmation or CoA from raw material suppliers.
- Document the screening result in the Product Information File (PIF).
Frequently asked questions
Source note for Annex II record Furazolidone (INN)
This page summarizes one Annex II record for Furazolidone (INN) from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex II conditions for Furazolidone (INN), but confirm any final regulatory decision against the current official annex wording and source files.
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