Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Annex II Entry 1694 CMR11/11/2022

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

Search similar Back to annex Compare
Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1694
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 13684-56-5
CAS 13684-56-5PubChem CID 24743

Desmedipham

Desmedipham is a carbamate ester that is phenylcarbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(ethoxycarbonyl)amino]phenyl group. It is an agrochemical used as a herbicide. It has a role as a herbicide, an agrochemical, a xenobiotic and an environmental contaminant. It is functionally related to a phenylcarbamic acid. — ChEBI

IUPAC name
[3-(ethoxycarbonylamino)phenyl] N-phenylcarbamate
Molecular formula
C16H16N2O4
Molecular weight
300.31 g/mol
Exact mass
300.11100700 Da
XLogP3
3.4
Topological polar surface area
76.7 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

BetanexBentanexBetanal AMSynbetan DSchering 38107DesmediphameBetanal AM 11Caswell No. 447AAA
16 more reported names
sn-38107EP-4753-Ethoxycarbonylaminophenyl-N-phenylcarbamateEthyl phenylcarbamoyloxyphenylcarbamateEthyl 3'-phenylcarbamoyloxycarbanilateSN 38107SN 475Carbanilic acid, m-carbaniloyloxy-, ethyl esterC7V2TTX346Carbanilic acid, m-hydroxy-, ethyl ester, carbanilate (ester)Ethyl meta-hydroxycarbanilate carbanilateSN 38170Ethyl m-hydroxycarbanilate carbanilate (ester)3-((Ethoxycarbonyl)amino)phenyl phenylcarbamateEthyl m-hydroxycarbanilate carbanilateCarbamic acid, phenylcarbamoyloxyphenyl-, ethyl ester
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate

Chemical / IUPAC name

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate

Regulatory information

Regulation

(EU) 2022/1531

See every entry this act set

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 2——✓

Key data

CAS
13684-56-5
EC
237-198-5
Annex
II
Entry number
1694

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1695
Nearby record in the same annex

Ammonium bromide

CAS: 12124-97-9
EC: 235-183-8

What Annex II means for Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 13684-56-5 is the unique numerical identifier assigned to Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
Open INCI Checker

Source note for Annex II record Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate

This page summarizes one Annex II record for Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate, but confirm any final regulatory decision against the current official annex wording and source files.

View sourcesView updates

Tools & next steps

Check your formula

Paste a full INCI list to detect Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate and other flagged EU annex records in one pass.

INCI Checker

Compare entries

Compare Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate side by side with another annex record to review differences in restrictions, concentrations and annex placement.

Compare

Browse the annex

See all records in Annex II and compare regulatory conditions across substances in this annex.

Open Annex II