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Annex II Entry 1622 CMR31/07/2020

1-Vinylimidazole

1-Vinylimidazole is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1622
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 1072-63-5
CAS 1072-63-5PubChem CID 66171

1-Vinylimidazole

IUPAC name
1-ethenylimidazole
Molecular formula
C5H6N2
Molecular weight
94.11 g/mol
Exact mass
94.053098200 Da
XLogP3
0.5
Topological polar surface area
17.8 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

N-Vinylimidazole1-ethenyl-1H-imidazole1H-Imidazole, 1-ethenyl-ODY9ION63AN-VI cpdRefChem:7907214-012-01-Vinyl-1H-imidazole
16 more reported names
Vinylimidazole1H-Imidazole, ethenyl-LufixanEINECS 214-012-0UNII-ODY9ION63ANSC 231574n-vinyl imidazoleN-vinyl-imidazoleUNII-J29LWK3XRM1-Vinyl-1H-imidazole #Imidazole N-1 deriv. 3EC 214-012-0VINYLIMIDAZOLE, 1-1-Vinylimidazole (Stabilized with Hydroquinone)1-Vinylimidazole, >=99%IMIDAZOLE, 1-VINYL-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:44575

1-ethenyl-1H-imidazole

A member of the class of imidazoles that is 1H-imidazole substituted by an ethenyl group at position 1. It is a reactive diluent in UV cured coatings.

Formula
C5H6N2
Average mass
94.117 g/mol
Monoisotopic mass
94.05310 Da
Formal charge
0
  • imidazoles — is a (CHEBI:24780)
  • olefinic compound — is a (CHEBI:78840)
  • 1H-imidazole — has functional parent (CHEBI:16069)
  • imidazoles — is a (CHEBI:24780)
  • olefinic compound — is a (CHEBI:78840)
Additional curated names
1-ethenyl-1H-imidazole1-ethenylimidazole1-vinyl-1H-imidazole1-vinylimidazoleN-vinylimidazole
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2026-06-04. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match66171

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

1-Vinylimidazole

Chemical / IUPAC name

1-Vinylimidazole

Regulatory information

Regulation

(EU) 2019/1966

See every entry this act set

Identified ingredients

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1B——✓

Key data

CAS
1072-63-5
EC
214-012-0
Annex
II
Entry number
1622

Inventory links for 1-Vinylimidazole

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

What Annex II means for 1-Vinylimidazole

1-Vinylimidazole is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. 1-Vinylimidazole is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 1072-63-5 is the unique numerical identifier assigned to 1-Vinylimidazole by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

1-Vinylimidazole has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record 1-Vinylimidazole

This page summarizes one Annex II record for 1-Vinylimidazole from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for 1-Vinylimidazole, but confirm any final regulatory decision against the current official annex wording and source files.

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