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Annex II Entry 1576 CMR30/07/2020

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1576
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 97-99-4
CAS 97-99-4PubChem CID 7360

Tetrahydrofurfuryl alcohol

Tetrahydrofurfuryl alcohol is a primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group. It has a role as a protic solvent. It is a primary alcohol and a member of oxolanes. — ChEBI

IUPAC name
oxolan-2-ylmethanol
Molecular formula
C5H10O2
Molecular weight
102.13 g/mol
Exact mass
102.068079557 Da
XLogP3
-0.1
Topological polar surface area
29.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Tetrahydro-2-furanmethanolTHFATetrahydro-2-furanylmethanol2-Furanmethanol, tetrahydro-QO ThfaFurfuryl alcohol, tetrahydro-Tetrahydro-2-furancarbinolTetrahydrofuryl carbinol
16 more reported names
2-(Hydroxymethyl)tetrahydrofuranTetrahydro-2-furfuryl alcoholTetrahydrofurylalkoholTetrahydro-2-furylmethanolTetrahydrofurfurylalkoholFEMA No. 3056NSC-15434CHEBI:137944RefChem:897174202-625-6(Tetrahydrofuran-2-yl)methanoltetrahydro furfuryl alcohol(oxolan-2-yl)methanoltetrahydrofuran-2-ylmethanolTetrahydrofurylmethanolOxolan-2-methanol
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

Chemical / IUPAC name

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

Identified ingredients

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1B——✓

Key data

CAS
97-99-4
EC
202-625-6
Annex
II
Entry number
1576

Inventory links for Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1575
Nearby record in the same annex

Styrene

CAS: 100-42-5
EC: 202-851-5
Annex II 1577
Nearby record in the same annex

Formaldehyde

CAS: 50-00-0
EC: 200-001-8
Annex II 1578
Nearby record in the same annex

Paraformaldehyde

CAS: 30525-89-4
EC: 608-494-5

What Annex II means for Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 97-99-4 is the unique numerical identifier assigned to Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol

This page summarizes one Annex II record for Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Tetrahydro-2-furylmethanol; tetrahydrofurfuryl alcohol, but confirm any final regulatory decision against the current official annex wording and source files.

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