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Annex II Entry 1445 CMR30/07/2020

Nickel oxalate [1]; Oxalic acid, nickel salt [2]

Nickel oxalate [1]; Oxalic acid, nickel salt [2] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1445
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 20543-06-0
CAS 20543-06-0CAS 547-67-1PubChem CID 68354

(Ethanedioato(2-)-kappaO1,kappaO2)nickel

IUPAC name
nickel(2+);oxalate
Molecular formula
C2NiO4
Molecular weight
146.71 g/mol
Exact mass
145.915000 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Nickel oxalate547-67-11OGH7H8HA9Nickel, (ethanedioato(2-)-kappaO1,kappaO2)-RefChem:1050961208-933-7nickel(II) oxalateNickel, [ethanedioato(2-)-.kappa.O1,.kappa.O2]-
16 more reported names
nickel(2+) oxalateOxalic acid, nickel saltEINECS 208-933-7UNII-1OGH7H8HA9EINECS 243-867-2Nickel(2+) ethanedioateEC 208-933-7NICKEL OXALATE [MI]NICKEL OXALATE (1:1)NICKEL OXALATE (NIC2O4)DOLZKNFSRCEOFV-UHFFFAOYSA-LETHANEDIOIC ACID, NICKEL SALTDB-255769OXALIC ACID, NICKEL(2+) SALT (1:1)ETHANEDIOIC ACID, NICKEL(2+) SALT (1:1)(ETHANEDIOATO(2-)-.KAPPA.O1,.KAPPA.O2)NICKEL
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Nickel oxalate [1]; Oxalic acid, nickel salt [2]

Chemical / IUPAC name

Nickel oxalate [1]; Oxalic acid, nickel salt [2]

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1A✓——

Key data

CAS
547-67-1 [1] 20543-06-0 [2]
EC
208-933-7 [1] 243-867-2 [2]
Annex
II
Entry number
1445

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1446
Nearby record in the same annex

Nickel telluride

CAS: 12142-88-0
EC: 235-260-6
Annex II 1441
Nearby record in the same annex

Nickel chromate

CAS: 14721-18-7
EC: 238-766-5
Annex II 1440
Nearby record in the same annex

Nickel dicyanide

CAS: 557-19-7
EC: 209-160-8

What Annex II means for Nickel oxalate [1]; Oxalic acid, nickel salt [2]

Nickel oxalate [1]; Oxalic acid, nickel salt [2] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Nickel oxalate [1]; Oxalic acid, nickel salt [2] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 547-67-1 [1] 20543-06-0 [2] is the unique numerical identifier assigned to Nickel oxalate [1]; Oxalic acid, nickel salt [2] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Nickel oxalate [1]; Oxalic acid, nickel salt [2] has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Nickel oxalate [1]; Oxalic acid, nickel salt [2]

This page summarizes one Annex II record for Nickel oxalate [1]; Oxalic acid, nickel salt [2] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Nickel oxalate [1]; Oxalic acid, nickel salt [2], but confirm any final regulatory decision against the current official annex wording and source files.

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