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Annex II Entry 1416 CMR30/07/2020

Cobalt di(acetate)

Cobalt di(acetate) is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1416
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 71-48-7
CAS 71-48-7PubChem CID 6277

Cobalt diacetate

Cobalt(II) acetate is a cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is acetate. It is a cobalt salt and an acetate salt. — ChEBI

IUPAC name
cobalt(2+) diacetate
Molecular formula
C4H6CoO4
Molecular weight
177.02 g/mol
Exact mass
176.959802 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

Cobalt(II) acetateCobalt acetateBis(acetato)cobaltCobaltous diacetateCOBALTOUS ACETATECobalt(2+) acetateCobalt di(acetate)Cobalt acetate (Co(OAc)2)
16 more reported names
3XC4P44U7ECHEBI:85138NSC-78410RefChem:578226lambda2-cobalt(2+) ion diacetate200-755-8cobalt(2+);diacetateAcetic acid, cobalt(2+) saltEINECS 200-755-8Acetic acid, cobalt(2+) salt (2:1)Bisacetic acid cobalt(II)CobaltacetateHSDB 997C4H6CoO4NSC 78410UNII-3XC4P44U7E
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Cobalt di(acetate)

Chemical / IUPAC name

Cobalt di(acetate)

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1B✓—✓
Cat. 2—✓—

Key data

CAS
71-48-7
EC
200-755-8
Annex
II
Entry number
1416

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1417
Nearby record in the same annex

Cobalt dinitrate

CAS: 10141-05-6
EC: 233-402-1
Annex II 1418
Nearby record in the same annex

Cobalt carbonate

CAS: 513-79-1
EC: 208-169-4
Annex II 1421
Nearby record in the same annex

Nickel matte

CAS: 69012-50-6
EC: 273-749-6

What Annex II means for Cobalt di(acetate)

Cobalt di(acetate) is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Cobalt di(acetate) is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 71-48-7 is the unique numerical identifier assigned to Cobalt di(acetate) by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Cobalt di(acetate) has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Cobalt di(acetate)

This page summarizes one Annex II record for Cobalt di(acetate) from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Cobalt di(acetate), but confirm any final regulatory decision against the current official annex wording and source files.

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