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CAS 672-76-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 9871412/10/2020

5-ISOPROPYLTROPOLONE

5-Isopropyltropolone

5-ISOPROPYLTROPOLONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 672-76-4

CAS 672-76-4PubChem CID 12649

Gamma-Thujaplicin

Gamma-Thujaplicin is a cyclic ketone. — ChEBI

IUPAC name: 2-hydroxy-5-propan-2-ylcyclohepta-2,4,6-trien-1-one

Molecular formula: C10H12O2
Molecular weight: 164.20 g/mol
Exact mass: 164.083729621 Da
XLogP3: 1.9
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-hydroxy-5-isopropyl-cyclohepta-2,4,6-trien-1-oneRefChem:1423665-Isopropyltropolonegamma-ThujaplicineTHUJAPLICIN, ALPHA.gamma.-Thujaplicin2,4,6-Cycloheptatrien-1-one, 2-hydroxy-5-(1-methylethyl)-.gamma.-Thujaplicine

16 more reported names

2-Hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one2,4,6-Cycloheptatrien-1-one, 2-hydroxy-5-isopropyl-CA2K6LJ2BV2-Hydroxy-5-isopropylcyclohepta-2,4,6-trien-1-oneNSC-18805NSC-43338NSC-402794WLN: L7VJ BQ EY1&12,6-Cycloheptatrien-1-one, 2-hydroxy-5-isopropyl-NSC 18805NSC 43338NSC 402794BRN 20443232,6-Cycloheptatrien-1-one, 2-hydroxy-5-(1-methylethyl)-AI3-28399|A-Thujaplicin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:10578
ChEMBL:CHEMBL1275999
EPA DTXSID:DTXSID2060969
PubMed:20947360
PubMed:17977717
PubMed:16418335
PubMed:15741178
PubMed:15467216
PubMed:11256489

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 5-ISOPROPYLTROPOLONE

INCI name

5-ISOPROPYLTROPOLONE

Description

5-Isopropyltropolone

Record provenance

Inventory reference: 98714
Imported identity: 5-ISOPROPYLTROPOLONE
Source update: 12/10/2020

European Commission CosIng source notes

Annex records for 5-ISOPROPYLTROPOLONE

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Key data

CAS

672-76-4

—

Restriction

—

Function

ANTICORROSIVE: Preventing and or inhibiting the corrosion of the packaging material.
ANTIMICROBIAL: Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#365 · 5-ISOPROPYLTROPOLONE

Ingredients with overlapping formulation functions

CHLOROUS ACIDANTICORROSIVE; ANTIMICROBIAL; DEODORANT; ORAL CARE; OXIDISING

CYCLOHEXYLAMINEANTICORROSIVE, BUFFERING

DIAMMONIUM PHOSPHATEANTICORROSIVE, BUFFERING, ORAL CARE

DILITHIUM OXALATEANTICORROSIVE, CHELATING

DIMETHYLAMINO METHYLPROPANOLANTICORROSIVE

DIPOTASSIUM OXALATEANTICORROSIVE, CHELATING

DIPOTASSIUM PHOSPHATEANTICORROSIVE, BUFFERING

DISODIUM DODECENYLSUCCINATEANTICORROSIVE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 5-ISOPROPYLTROPOLONE appears in the CosIng inventory

The CosIng inventory lists 5-ISOPROPYLTROPOLONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

5-ISOPROPYLTROPOLONE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

5-ISOPROPYLTROPOLONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 5-ISOPROPYLTROPOLONE carries the following function designation(s):

CAS 672-76-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 5-ISOPROPYLTROPOLONE

This page reproduces the CosIng inventory entry for 5-ISOPROPYLTROPOLONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 5-ISOPROPYLTROPOLONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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