What other records share CAS 521-35-7?

CAS 521-35-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9821307/07/2020

CANNABINOL

Q: What does the restriction note for CANNABINOL mean?

The restriction field for CANNABINOL reads: II/306 CANNABINOL, as such, is not listed in the Schedules of the 1961 Single Convention on Narcotic Drugs. However, it shall be prohibited from use in cosmetic products (II/306), if prepared from a substance controlled in Schedule I of the 1961 Single Convention on Narcotic Drugs. Please note that national legislations on controlled substances may also apply.. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

Cannabinol is the organic compound that conforms to the formula:

CANNABINOL is linked to 1 EU annex record on this page. Inventory note: II/306 CANNABINOL, as such, is not listed in the Schedules of the 1961 Single Convention on Narcotic Drugs. However, it shall be prohibited from use in cosmetic products (II/306), if prepared from a substance controlled in Schedule I of the 1961 Single Convention on Narcotic Drugs. Please note that national legislations on controlled substances may also apply..

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Evidence linked Prohibited Open this evidence	1	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 521-35-7

CAS 521-35-7PubChem CID 2543

Cannabinol

Cannabinol is a dibenzopyran. — ChEBI

IUPAC name: 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol

Molecular formula: C21H26O2
Molecular weight: 310.4 g/mol
Exact mass: 310.193280068 Da
XLogP3: 6.1
Topological polar surface area: 29.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

CannabinoloCannabinolum6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol7UYP6MC9GH6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo(b,d)pyran6H-Dibenzo(b,d)pyran-1-ol, 6,6,9-trimethyl-3-pentyl-NSC-134455

16 more reported names

3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran6H-Dibenzo[b,d]pyran-1-ol, 6,6,9-trimethyl-3-pentyl-6,6,9-trimethyl-3-pentylbenzo(c)chromen-1-olRefChem:388855Cannabinolo [DCIT]Cannabinol (CBN)Cannabinolum [INN-Latin]6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-olCannabinol [INN:BAN]NSC 134455UNII-7UYP6MC9GHBRN 02371453-Amyl-1-hydroxy-6,6 ,9-trimethyl-6H-dibenzo[b,d]pyranCannabinol; 3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran; 6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol; CBN; NSC 134455; CannabinoidsCannabinol (6CI)CANNABINOL [MI]

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:3360
ChEMBL:CHEMBL74415
EPA DTXSID:DTXSID3048996
PubMed:40706771
PubMed:39835903
PubMed:38263462
PubMed:31154070
PubMed:31096838
PubMed:29689453
PubMed:19910459
PubMed:19679411
PubMed:18619955
PubMed:18550765
PubMed:16805813
PubMed:15380375

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CANNABINOL

INCI name

CANNABINOL

Description

Cannabinol is the organic compound that conforms to the formula:

Record provenance

Inventory reference: 98213
Imported identity: CANNABINOL
Source update: 07/07/2020

European Commission CosIng source notes

Annex records for CANNABINOL

Annex II Restriction reference

Entry 306

Narcotics, natural and synthetic: All substances listed in Tables I and II of the Single Convention…

Key data

CAS

521-35-7

689-788-0

Restriction

II/306 CANNABINOL, as such, is not listed in the Schedules of the 1961 Single Convention on Narcotic Drugs. However, it shall be prohibited from use in cosmetic products (II/306), if prepared from a substance controlled in Schedule I of the 1961 Single Convention on Narcotic Drugs. Please note that national legislations on controlled substances may also apply.

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5256 · CANNABINOL

Ingredients with overlapping formulation functions

CANNABIDIOL - DERIVED FROM EXTRACT OR TINCTURE OR RESIN OF CANNABISANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

CANNABIDIOL - SYNTHETICALLY PRODUCEDANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

CANNABIGEROLSKIN CONDITIONING

CANNABINOIDSSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

CANNABIS SATIVA CALLUS CULTURE LYSATE EXTRACTHAIR CONDITIONING, SKIN CONDITIONING

CANNABIS SATIVA CALLUS LYSATESKIN CONDITIONING

CANNABIS SATIVA FLOWER EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

CANNABIS SATIVA FLOWER/LEAF/STEM EXTRACTANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CANNABINOL appears in the CosIng inventory

The CosIng inventory lists CANNABINOL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CANNABINOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CANNABINOL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CANNABINOL reads: "II/306 CANNABINOL, as such, is not listed in the Schedules of the 1961 Single Convention on Narcotic Drugs. However, it shall be prohibited from use in cosmetic products (II/306), if prepared from a substance controlled in Schedule I of the 1961 Single Convention on Narcotic Drugs. Please note that national legislations on controlled substances may also apply.". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CANNABINOL carries the following function designation(s):

SKIN CONDITIONING

CAS 521-35-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CANNABINOL

This page combines the CosIng inventory entry for CANNABINOL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CANNABINOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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