What function does (20S)-PROTOPANAXADIOL serve in cosmetics?

According to the EU CosIng inventory, (20S)-PROTOPANAXADIOL carries the following function designation(s): SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING.

What other records share CAS 30636-90-9?

CAS 30636-90-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains (20S)-PROTOPANAXADIOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9815830/04/2020

(20S)-PROTOPANAXADIOL

(20S)-PROTOPANAXADIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 30636-90-9

CAS 30636-90-9PubChem CID 11213350

(20S)-Protopanaxadiol

(20S)-protopanaxadiol is a diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-S position. — ChEBI

IUPAC name: (3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol

Molecular formula: C30H52O3
Molecular weight: 460.7 g/mol
Exact mass: 460.39164552 Da
XLogP3: 7.2
Topological polar surface area: 60.7 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 10

Also known as

20-Epiprotopanaxadiol20(S)-APPDdammar-24-ene-3beta,12beta,20-triolMR8AEF5T1NUNII-MR8AEF5T1NDammar-24-ene-3,12,20-triol, (3beta,12beta)-CHEBI:7595024-dammarene-3beta,12beta,20S-triol

16 more reported names

dammar-24-ene-3beta,12beta,20S-triol(20S)-protopanaxadiol-type ginsenoside aglyconeDAMMAR-24-ENE-3.BETA.,12.BETA.,20-TRIOLDAMMAR-24-ENE-3,12,20-TRIOL, (3.BETA.,12.BETA.)-RefChem:6863720(S)-protopanaxadiol(20S)-ProtopanaxdiolProtopanasadiolDammar-24-ene-3ss,12ss,20-triol; (20S)-Protopanaxadiol; 20(S)-APPD; 20-Epiprotopanaxadiol; (3ss,12ss)-Dammar-24-ene-3,12,20-triol;20(S)Protopanaxdiol(20S)-Protopanaxadiol?PYXFVCFISTUSOO-HKUCOEKDSA-NHMS3885P20HMS6019D08HY-N0797Protopanaxadiol, analytical standard

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:75950
ChEMBL:CHEMBL375563
EPA DTXSID:DTXSID10952905

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label is a composite INCI name with 2 named source-material segments. Each segment must be reconciled with the supplier specification.

Identity type from wording: composite

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for (20S)-PROTOPANAXADIOL

INCI name

(20S)-PROTOPANAXADIOL

Record provenance

Inventory reference: 98158
Imported identity: (20S)-PROTOPANAXADIOL
Source update: 30/04/2020

European Commission CosIng source notes

Annex records for (20S)-PROTOPANAXADIOL

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Key data

CAS

30636-90-9

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Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#1 · (20S)-PROTOPANAXADIOL

Ingredients with overlapping formulation functions

(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FE…ANTI-SEBUM, ANTIOXIDANT, SKIN PROTECTING

(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS …HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRI…ANTI-SEBORRHEIC, ANTI-SEBUM, ANTIOXIDANT, SKIN PROTECTING

(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMO…HUMECTANT, SKIN CONDITIONING - HUMECTANT, SKIN PROTECTING

(BROCCOLI/ERUCA SATIVA/LEPIDIUM SATIVUM/NASTURTIUM OFFICINALE/RADISH) SPROUT EX…SKIN CONDITIONING, SKIN PROTECTING

(CODONOPSIS TANGSHEN/DIOSCOREA JAPONICA) ROOT/ATRACTYLODES JAPONICA RHIZOME/POR…HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

(LAVANDULA ANGUSTIFOLIA/MELISSA OFFICINALIS/HYPERICUM PERFORATUM) FLOWER/(CAMEL…ANTI-SEBUM, ANTIMICROBIAL, SKIN CONDITIONING, SKIN PROTECTING

(LEPIDIUM MEYENII/SARCODON ASPRATUS) ROOT WATERANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How (20S)-PROTOPANAXADIOL appears in the CosIng inventory

The CosIng inventory lists (20S)-PROTOPANAXADIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

(20S)-PROTOPANAXADIOL is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

(20S)-PROTOPANAXADIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, (20S)-PROTOPANAXADIOL carries the following function designation(s):

CAS 30636-90-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for (20S)-PROTOPANAXADIOL

This page reproduces the CosIng inventory entry for (20S)-PROTOPANAXADIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research (20S)-PROTOPANAXADIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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