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InventoryRef 9736111/10/2019

BUTENEDIOL

2-Butene-1,4-diol

BUTENEDIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 110-64-5
CAS 110-64-5PubChem CID 8065

2-Butene-1,4-diol

IUPAC name
but-2-ene-1,4-diol
Molecular formula
C4H8O2
Molecular weight
88.11 g/mol
Exact mass
88.052429494 Da
XLogP3
-0.8
Topological polar surface area
40.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Butenediol1,4-DIHYDROXY-2-BUTENENSC-976RefChem:570515203-787-02I323Z5567Agrisynth B2DNSC-1260
12 more reported names
2-Butene-1,4-diol(cis+trans)2-Buten-1,4-diolZ/E-But-2-ene-1,4-diorac-2-?Butene-?1,?4-?diol(Z)2-Butene-1,4-Diol1,4dihydroxybut-2-ene98% (GC)(isomers mixture)cis,trans-2-Buten-1,4-diolB08112-Butene-1,4-diol (mixture of cis and trans)1,4-Dihydroxy-2-butene (cis-and trans-mixture)rac-1,4-Dihydroxy-2-butene; rac-1,4-Dihydroxybutene; rac-NSC 1260; rac-NSC 976
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8065

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (91.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (89.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (84.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 46 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P264, P270, P273, P301+P317, P330, and P501 (click each P-code to see the statement) Source: NITE-CMC

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BUTENEDIOL

INCI name

BUTENEDIOL

Description

2-Butene-1,4-diol

Record provenance

Inventory reference
97361
Imported identity
BUTENEDIOL
Source update
11/10/2019
European Commission CosIng source notes
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Key data

CAS
110-64-5
EC
203-787-0
Restriction
—
Function
NOT REPORTED
No function currently reported.

Ingredients with overlapping formulation functions

BORONOPHENYLALANINE HCLNOT REPORTED
BUDDLEJA DAVIDII CALLUS EXTRACTNOT REPORTED
BUTADIENENOT REPORTED
BUTENENOT REPORTED
BUTYL MALEATENOT REPORTED
BUTYLDIMETHICONYL PROPOXYETHYLCARBAMOYLPROPYL SILSESQUIOXANENOT REPORTED
C1-18 ALKYL ACRYLATENOT REPORTED
C1-2 ALKYL SUCCINATENOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How BUTENEDIOL appears in the CosIng inventory

The CosIng inventory lists BUTENEDIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BUTENEDIOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BUTENEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BUTENEDIOL carries the following function designation(s):

CAS 110-64-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for BUTENEDIOL

This page reproduces the CosIng inventory entry for BUTENEDIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BUTENEDIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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