Is TOSYL VALINE safe to use in EU cosmetics?

TOSYL VALINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 17360-25-7?

CAS 17360-25-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TOSYL VALINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9731023/10/2019

TOSYL VALINE

L-Valine, N-[(4-methylphenyl)sulfonyl]-

TOSYL VALINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 17360-25-7

CAS 17360-25-7PubChem CID 2249310

Tosyl valine

IUPAC name: (2S)-3-methyl-2-[(4-methylphenyl)sulfonylamino]butanoic acid

Molecular formula: C12H17NO4S
Molecular weight: 271.33 g/mol
Exact mass: 271.08782920 Da
XLogP3: 2.2
Topological polar surface area: 91.9 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

n-tosylvalineKX49VS36SI(2S)-3-methyl-2-{[(4-methylphenyl)sulfonyl]amino}butanoic acidL-Valine, N-((4-methylphenyl)sulfonyl)-(2S)-3-Methyl-2-([(4-methylphenyl)sulfonyl]amino)butanoic acidNSC-142791L-Valine, N-[(4-methylphenyl)sulfonyl]-(2S)-3-Methyl-2-(((4-methylphenyl)sulfonyl)amino)butanoic acid

16 more reported names

RefChem:1100192(2S)-3-methyl-2-(4-methylbenzenesulfonamido)butanoic acidN-p-Toluenesulfonyl-l-valine(S)-3-Methyl-2-(4-methylbenzenesulfonamido)butanoic acid(S)-3-methyl-2-(4-methylphenylsulfonamido)butanoic acidtosyl-L-valineTosyl valine [INCI]UNII-KX49VS36SIN-(p-toluenesulfonyl)valineNCIStruc1_000618NCIStruc2_0004063-METHYL-2-([(4-METHYLPHENYL)SULFONYL]AMINO)BUTANOIC ACIDCCG-38103N-[(4-Methylphenyl)sulfonyl]valine #NSC 142791AS-94845

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1410826

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TOSYL VALINE

INCI name

TOSYL VALINE

Description

L-Valine, N-[(4-methylphenyl)sulfonyl]-

Record provenance

Inventory reference: 97310
Imported identity: TOSYL VALINE
Source update: 23/10/2019

European Commission CosIng source notes

Annex records for TOSYL VALINE

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Key data

CAS

17360-25-7

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Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28983 · TOSYL VALINE

Ingredients with overlapping formulation functions

TILLANDSIA USNEOIDES CALLUS EXTRACTANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

TITANIUM BIS-LACTATE DIHYDROXIDEADHESIVE, BINDING, HAIR CONDITIONING

TOCOPHERYL ETHYL SUCCINATE ETHYLDIMONIUM ETHOSULFATEHAIR CONDITIONING, SKIN CONDITIONING

TOCOPHERYL PHOSPHATECLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

TRAMETES VERSICOLOR EXTRACTHAIR CONDITIONING

TREHALOSE HYDROXYPROPYLTRIMONIUM CHLORIDEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

TREHALOSE UNDECYLENOATECLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

TREMELLA FUCIFORMIS SPOROCARP EXTRACTANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TOSYL VALINE appears in the CosIng inventory

The CosIng inventory lists TOSYL VALINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TOSYL VALINE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TOSYL VALINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TOSYL VALINE carries the following function designation(s):

CAS 17360-25-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TOSYL VALINE

This page reproduces the CosIng inventory entry for TOSYL VALINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TOSYL VALINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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