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InventoryRef 9694313/05/2019

HYDRANGENOL

1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-(4-hydroxyphenyl)-

HYDRANGENOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 480-47-7
CAS 480-47-7PubChem CID 119199

3,4-dihydro-8-hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one

Hydrangenol is a member of the class of dihydroisocoumarins that is 3,4-dihydroisocoumarin substituted by a hydroxy group at position 8 and a 4-hydroxyphenyl group at position 3. It has been isolated from the roots of Scorzonera judaica and exhibits anti-allergic activity. It has a role as an anti-allergic agent and a plant metabolite. It is a member of phenols and a member of dihydroisocoumarins. It is functionally related to a 3,4-dihydroisocoumarin. ChEBI

IUPAC name
8-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroisochromen-1-one
Molecular formula
C15H12O4
Molecular weight
256.25 g/mol
Exact mass
256.07355886 Da
XLogP3
3.2
Topological polar surface area
66.8 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

HydrangenolTL8PI7PHV11H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-(4-hydroxyphenyl)-CHEBI:57768-hydroxy-3-(4-hydroxyphenyl)isochroman-1-oneRefChem:1469848-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-1H-2-benzopyran-1-oneAC1L3ODH
16 more reported names
UNII-TL8PI7PHV1CCRIS 8569Isocoumarin, 3,4-dihydro-8-hydroxy-3-(p-hydroxyphenyl)- (6CI,7CI,8CI); 3,4-Dihydro-8-hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one; (+/-)-HydrangenolHYDRANENOL(+/-)-Hydrangenol(A+/-)-Hydrangenol8-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-1h-isochromen-1-oneCHEBI:68140HY-N4028TN4234EBC-616608FS-9918DA-54150CS-0024477ISOCOUMARIN, 3,4-DIHYDRO-8-HYDROXY-3-(P-HYDROXYPHENYL)-Isocoumarin, 3,4-dihydro-8-hydroxy-3-(p-hydroxyphenyl)- (6CI,7CI,8CI); 3,4-Dihydro-8-hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one; ()-Hydrangenol
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDRANGENOL

INCI name

HYDRANGENOL

Description

1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-(4-hydroxyphenyl)-

Record provenance

Inventory reference
96943
Imported identity
HYDRANGENOL
Source update
13/05/2019
European Commission CosIng source notes

Key data

EC
Restriction
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How HYDRANGENOL appears in the CosIng inventory

The CosIng inventory lists HYDRANGENOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDRANGENOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDRANGENOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HYDRANGENOL carries the following function designation(s):

CAS 480-47-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for HYDRANGENOL

This page reproduces the CosIng inventory entry for HYDRANGENOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HYDRANGENOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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