What function does DEOXYCHOLIC ACID serve in cosmetics?

According to the EU CosIng inventory, DEOXYCHOLIC ACID carries the following function designation(s): HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT.

What other records share CAS 83-44-3?

CAS 83-44-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains DEOXYCHOLIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9686815/04/2019

DEOXYCHOLIC ACID

DEOXYCHOLIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 83-44-3

CAS 83-44-3PubChem CID 222528

Deoxycholic Acid

Deoxycholic acid is a bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively. It has a role as a human blood serum metabolite. It is a C24-steroid, a dihydroxy-5beta-cholanic acid and a bile acid. It is a conjugate acid of a deoxycholate. — ChEBI

IUPAC name: (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

Molecular formula: C24H40O4
Molecular weight: 392.6 g/mol
Exact mass: 392.29265975 Da
XLogP3: 4.9
Topological polar surface area: 77.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 10

Also known as

CholerebicCholeic acidCholorebicDegalolDroxolanDeoxycholatic acidPyrocholSeptochol

16 more reported names

Desoxycholsaeure7-Deoxycholic acid7alpha-Deoxycholic acid3alpha,12alpha-Dihydroxy-5beta-cholanic acidCholic acid, deoxy-3,12-Dihydroxycholanic acidATX-101Dihydroxycholanoic acidDeoxy cholic acid3alpha,12alpha-Dihydroxy-5beta-cholan-24-oic acid(3alpha,5beta,12alpha)-3,12-Dihydroxycholan-24-oic acidacido desoxicolicoNSC-8797acide desoxycholiqueDWJ211DWJ-211

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:28834
ChEMBL:CHEMBL406393
EPA DTXSID:DTXSID0042662
PubMed:41563640
PubMed:25724831
PubMed:25684122
PubMed:23094082
PubMed:23066200
PubMed:23059904
PubMed:23049867
PubMed:23003564
PubMed:22988238
PubMed:22978462
PubMed:22952616
PubMed:22939256

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DEOXYCHOLIC ACID

INCI name

DEOXYCHOLIC ACID

Description

(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic Acid; 3,12-dihydroxycholan-24-oic acid; 3-α,12-α-Dihydroxy-5-β-cholan-24-oic acid; Deoxycholic Acid; Desoxycholic aci

Record provenance

Inventory reference: 96868
Imported identity: DEOXYCHOLIC ACID
Source update: 15/04/2019

European Commission CosIng source notes

Annex records for DEOXYCHOLIC ACID

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Key data

CAS

83-44-3

201-478-5

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8352 · DEOXYCHOLIC ACID

Ingredients with overlapping formulation functions

DENDROBIUM CANDIDUM CALLUS POWDERANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

DENDROBIUM CANDIDUM STEM EXTRACTHUMECTANT, SKIN CONDITIONING

DENDROBIUM LODDIGESII LEAF/STEM EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

DENDROPANAX MORBIFERUS ADVENTITIOUS ROOT EXTRACTANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN PROTECTING

DEOXYGLUTAMYL FRUCTOSEHUMECTANT, NAIL CONDITIONING, SKIN CONDITIONING

DERBESIA MARINA EXTRACTHUMECTANT, SKIN CONDITIONING

DERMACOCCUS PROFUNDI LYSATE EXTRACTHAIR CONDITIONING; HUMECTANT; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

DESMARESTIA TABACOIDES EXTRACTHUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DEOXYCHOLIC ACID appears in the CosIng inventory

The CosIng inventory lists DEOXYCHOLIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DEOXYCHOLIC ACID is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DEOXYCHOLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DEOXYCHOLIC ACID carries the following function designation(s):

CAS 83-44-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DEOXYCHOLIC ACID

This page reproduces the CosIng inventory entry for DEOXYCHOLIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DEOXYCHOLIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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