InventoryRef 9670425/04/2019

R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER

Q: How do I check if my formula contains R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER?

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Inventory details for R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER

INCI name

R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER

Description

This peptide is a dimer linked by a disulfide bridge between the cysteines, consisting of a single chain synthetic fusion peptide, produced by fermentation in Chinese Hamster Ovary (CHO). The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-111, Oligopeptide-163, sh-Polypeptide-117, sh-Polypeptide-94, sh-Polypeptide-95, and Pentapeptide-63. This fusion protein binds to Immunoglobulin E (IgE) and Interleukin-10 (IL-10) receptors; and it contains 605 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 amino acids.

Annex records for R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER

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Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

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Search the annex database for entries matching R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER or related substances.

Key data

CAS

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Restriction

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Function

SKIN CONDITIONING SKIN CONDITIONING - EMOLLIENT SKIN PROTECTING

How R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER appears in the CosIng inventory

The CosIng inventory lists R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER carries the following function designation(s):

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Source note for R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER

This page reproduces the CosIng inventory entry for R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research R-(SH-POLYPEPTIDE-111 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-117 SH-POLYPEPTIDE-94 SH-POLYPEPTIDE-95 PENTAPEPTIDE-63 OLIGOPEPTIDE-163 SH-POLYPEPTIDE-6) DIMER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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