Is GEMFIBROZIL safe to use in EU cosmetics?

GEMFIBROZIL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 25812-30-0?

CAS 25812-30-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains GEMFIBROZIL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9615320/04/2018

GEMFIBROZIL

Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-

GEMFIBROZIL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 25812-30-0

CAS 25812-30-0PubChem CID 3463

Gemfibrozil

Gemfibrozil is an aromatic ether. It has a role as an antilipemic drug. It is functionally related to a valeric acid. — ChEBI

IUPAC name: 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid

Molecular formula: C15H22O3
Molecular weight: 250.33 g/mol
Exact mass: 250.15689456 Da
XLogP3: 3.8
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

LopidLipurJezilCI-719GemfibrozilumGemfibroziloGemlipidPentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-

16 more reported names

2,2-Dimethyl-5-(2,5-xylyloxy)valeric acidGen-Fibro2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeureCI 7192,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeureNSC-757024Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-GemfibrosilQ8X02027X3CHEBI:5296Lopid RApoGemfibrozilGenGemfibrozilGenlipNuGemfibrozilApo Gemfibrozil

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:5296
ChEMBL:CHEMBL457
EPA DTXSID:DTXSID0020652
PubMed:34520103
PubMed:33814510
PubMed:32808185
PubMed:32741897
PubMed:31424850
PubMed:30853469
PubMed:29960002
PubMed:28743512
PubMed:28108177
PubMed:27665778
PubMed:27506419
PubMed:27462272

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GEMFIBROZIL

INCI name

GEMFIBROZIL

Description

Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-

Record provenance

Inventory reference: 96153
Imported identity: GEMFIBROZIL
Source update: 20/04/2018

European Commission CosIng source notes

Annex records for GEMFIBROZIL

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching GEMFIBROZIL or related substances.

Key data

CAS

25812-30-0

657-339-8

Restriction

—

Function

NOT REPORTED: No function currently reported.

Ingredients with overlapping formulation functions

FISH CARTILAGE EXTRACTNOT REPORTED

FISH EXTRACTNOT REPORTED

FLUORENONENOT REPORTED

GANODERMA LUCIDUM POWDERNOT REPORTED

GLYCERYL LACTATENOT REPORTED

GLYCERYL LAURATE DIACETATENOT REPORTED, SKIN CONDITIONING

GOAT MILK EXTRACTNOT REPORTED

GOLD ACETYLMETHIONATENOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GEMFIBROZIL appears in the CosIng inventory

The CosIng inventory lists GEMFIBROZIL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GEMFIBROZIL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GEMFIBROZIL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GEMFIBROZIL carries the following function designation(s):

NOT REPORTED

CAS 25812-30-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for GEMFIBROZIL

This page reproduces the CosIng inventory entry for GEMFIBROZIL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GEMFIBROZIL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect GEMFIBROZIL and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to GEMFIBROZIL, its identifiers or nearby name variants.