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InventoryRef 9593624/04/2018

DIETHYL CARBONATE

Carbonic acid, diethyl ester

DIETHYL CARBONATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 105-58-8
CAS 105-58-8PubChem CID 7766

Diethyl Carbonate

Diethyl carbonate appears as a colorless liquid with a mild pleasant odor. It is slightly less dense than water and insoluble in water. Hence floats on water. Flash point 77 °F. Vapors are heavier than air. When heated to high temperatures it may emit acrid smoke. Used as a solvent. — CAMEO Chemicals

IUPAC name
diethyl carbonate
Molecular formula
C5H10O3
Molecular weight
118.13 g/mol
Exact mass
118.062994177 Da
XLogP3
1.2
Topological polar surface area
35.5 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Ethyl carbonateCarbonic acid diethyl esterEufinCarbonic acid, diethyl esterDiatolCarbonic etherDiaethylcarbonatDiethylkarbonat
16 more reported names
Ethyl carbonate ((EtO)2CO)NCI-C60899Diethylester kyseliny uhlicite3UA92692HGNSC-8849RefChem:133406203-311-1diethylcarbonateDiethyl carbonate-13C5NSC 8849Diethylcarbonate, 99%ethyl ethoxyformateDiethylkarbonat [Czech]Diaethylcarbonat [German]CCRIS 6229HSDB 925
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:173463

Diethyl carbonate

Formula
C5H10O3
Average mass
118.132 g/mol
Monoisotopic mass
118.06299 Da
Formal charge
0
  • carbonate ester — is a (CHEBI:46722)
  • carbonate ester — is a (CHEBI:46722)
Additional curated names
diethyl carbonate
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7766

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • ERG2024, Guide 128 (Diethyl carbonate): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • Note: This chemical does not meet GHS hazard criteria for 2.9% (12 of 412) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H226 (97.1%): Flammable liquid and vapor [Warning Flammable liquids]; H315 (13.8%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (14.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (13.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 412 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 412 reports by companies.; There are 12 notifications provided by 400 of 412 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]; H315 (97.4%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (97.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (97.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 2 was calculated for diethyl carbonate(SRC), using a log Kow of 1.21(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 100(SRC), determined from a log Kow of 1.21(2) and a regression-derived equation(3), indicates that diethyl carbonate is expected to have high mobility in soil(SRC). Volatilization of diethyl carbonate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 8.9X10-5 atm-cu m/mole(SRC), calculated from a vapor pressure of 10.8 mm Hg(4) and water solubility of 18,800 mg/l(5). Diethyl carbonate may volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Although no biodegradation data for diethyl carbonate was located, chemically similar short alkyl chain esters have been shown to biodegrade(6). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 100(SRC), determined from a log Kow of 1.21(2) and a regression-derived equation(3), indicates that diethyl carbonate is not expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is expected to be an important fate process(3) based upon an estimated Henry's Law constant of 8.9X10-5 atm-cu m/mole(SRC), calculated from a vapor pressure of 10.8 mm Hg(4) and water solubility of 18,800 mg/l(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 8 hours and 8 days, respectively(SRC). Diethyl carbonate may undergo hydrolysis in water since esters are susceptible to hydrolysis(3). Although no biodegradation data for diethyl carbonate was located, chemically similar short alkyl chain esters have been shown to biodegrade(6). According to a classification scheme(7), an estimated BCF of 2(SRC), from its log Kow(2) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethyl carbonate, which has a vapor pressure of 10.8 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethyl carbonate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 5 days(SRC), calculated from its estimated rate constant of 3.3X10-12 cu cm/molecule-sec at 25 °C(SRC) determined using a structure estimation method(3). Diethyl carbonate may also undergo direct photolysis in the environment since this compound contains a functional group that can absorb light greater than 290 nm(4). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIETHYL CARBONATE

INCI name

DIETHYL CARBONATE

Description

Carbonic acid, diethyl ester

Record provenance

Inventory reference
95936
Imported identity
DIETHYL CARBONATE
Source update
24/04/2018
European Commission CosIng source notes
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Key data

CAS
105-58-8
EC
203-311-1
Restriction
—
Function
NOT REPORTED
No function currently reported.

Ingredients with overlapping formulation functions

DECYL POLYSTYRENE OXIDE/PEG-23 COPOLYMER PHOSPHATENOT REPORTED
DELTA-VALEROLACTONENOT REPORTED
DELTAMETHRINNOT REPORTED
DIALLYLDIMETHYL AMMONIUM CHLORIDENOT REPORTED
DIETHYLENETRIAMINENOT REPORTED
DIISOBUTYLENENOT REPORTED
DIISOPROPYL HEPTYL PHOSPHINE OXIDENOT REPORTED
DILINOLEYL ALCOHOLNOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DIETHYL CARBONATE appears in the CosIng inventory

The CosIng inventory lists DIETHYL CARBONATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIETHYL CARBONATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIETHYL CARBONATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DIETHYL CARBONATE carries the following function designation(s):

CAS 105-58-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DIETHYL CARBONATE

This page reproduces the CosIng inventory entry for DIETHYL CARBONATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DIETHYL CARBONATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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