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CAS 38260-01-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 9559118/04/2018

TRIETHYLENETETRAMINE HCL

1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)-, hydrochloride (1:2),Trientine Hydrochloride

TRIETHYLENETETRAMINE HCL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 38260-01-4

CAS 38260-01-4PubChem CID 71433

Trientine Hydrochloride

Trientine hydrochloride is a secondary amino compound. — ChEBI

IUPAC name: N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride

Molecular formula: C6H20Cl2N4
Molecular weight: 219.15 g/mol
Exact mass: 218.1065020 Da
Topological polar surface area: 76.1 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 4
Covalent units: 3
Defined stereocentres: 0

Also known as

Triethylenetetramine dihydrochlorideTrientine DihydrochlorideSyprineMK-0681Triethylene tetramine dihydrochloride1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, dihydrochlorideMetaliteHC3NX54582

16 more reported names

NSC-759164CLOVIQUEN,N'-bis(2-aminoethyl)ethane-1,2-diamine dihydrochlorideRefChem:57637N,N-bis (2-aminoethyl)-1,2-ethanediamine Dihydrochloride253-854-3N,N'-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochlorideN1,N1'-(ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochlorideTrien dihydrochlorideCupridC6H20Cl2N4Trientine hydrochloride [USAN]Triethylenetetramine 2HClEINECS 253-854-3MK 0681Laszarin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:9706
ChEMBL:CHEMBL3989777
EPA DTXSID:DTXSID2057863

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRIETHYLENETETRAMINE HCL

INCI name

TRIETHYLENETETRAMINE HCL

Description

1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)-, hydrochloride (1:2),Trientine Hydrochloride

Record provenance

Inventory reference: 95591
Imported identity: TRIETHYLENETETRAMINE HCL
Source update: 18/04/2018

European Commission CosIng source notes

Annex records for TRIETHYLENETETRAMINE HCL

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Key data

CAS

38260-01-4

—

Restriction

—

Function

CHELATING: Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29172 · TRIETHYLENETETRAMINE HCl

Ingredients with overlapping formulation functions

TETRASODIUM PYROPHOSPHATEANTICAKING, BUFFERING, CHELATING, ORAL CARE

TEUPOLIOSIDEANTIOXIDANT, BLEACHING, CHELATING, SKIN PROTECTING

THIOHISTIDINEANTIOXIDANT, BLEACHING, CHELATING

TITANIUM TETRAGLYCEROXIDECHELATING, HUMECTANT, ORAL CARE, SKIN CONDITIONING

TRIMETHOXYBENZYLIDENE PENTANEDIONEANTIOXIDANT, CHELATING, SKIN PROTECTING

TRIMETHYLDECENEDIONEBLEACHING, CHELATING

TRIMETHYLOLPROPANE HYDROXYPROPYL BIS-HYDROXYETHYLAMINE DENDRIMERCHELATING, CLEANSING, SURFACTANT - CLEANSING

TRIPOTASSIUM EDTACHELATING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TRIETHYLENETETRAMINE HCL appears in the CosIng inventory

The CosIng inventory lists TRIETHYLENETETRAMINE HCL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIETHYLENETETRAMINE HCL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIETHYLENETETRAMINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRIETHYLENETETRAMINE HCL carries the following function designation(s):

CHELATING

CAS 38260-01-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TRIETHYLENETETRAMINE HCL

This page reproduces the CosIng inventory entry for TRIETHYLENETETRAMINE HCL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRIETHYLENETETRAMINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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