Is HEA SUCCINATE safe to use in EU cosmetics?

HEA SUCCINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 50940-49-3?

CAS 50940-49-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains HEA SUCCINATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9441517/08/2016

HEA SUCCINATE

Acryloyloxyethyl Succinate,Butanedioic acid, 1-[2-[(1-oxo-2-propen-1-yl)oxy]ethyl] ester

HEA SUCCINATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 50940-49-3

CAS 50940-49-3PubChem CID 175956

Acryloyloxyethyl succinate

IUPAC name: 4-oxo-4-(2-prop-2-enoyloxyethoxy)butanoic acid

Molecular formula: C9H12O6
Molecular weight: 216.19 g/mol
Exact mass: 216.06338810 Da
XLogP3: 0.0
Topological polar surface area: 89.9 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 0

Also known as

2-(Acryloyloxy)ethyl Hydrogen SuccinateButanedioic acid, 1-(2-((1-oxo-2-propen-1-yl)oxy)ethyl) esterButanedioic acid, 1-[2-[(1-oxo-2-propen-1-yl)oxy]ethyl] esterRefChem:552879478-130-6610-591-24-(2-(Acryloyloxy)ethoxy)-4-oxobutanoic acidmonoacryloyloxyethyl succinate

16 more reported names

Mono(2-acryloyloxyethyl) succinate (stabilized with MEHQ)Q9AZV5U0FH4-[2-(Acryloyloxy)ethoxy]-4-oxobutanoic acid4-OXO-4-[2-(PROP-2-ENOYLOXY)ETHOXY]BUTANOIC ACIDButanedioic acid, mono(2-((1-oxo-2-propenyl)oxy)ethyl) esterButanedioic acid, mono[2-[(1-oxo-2-propenyl)oxy]ethyl] esterHEA SUCCINATEUNII-Q9AZV5U0FHSuccinic acid monoacryloyloxyethyl esterMono(2-acryloyloxyethyl) SuccinateNK ESTER A-SASuccinic Acid Mono(2-acryloyloxyethyl) EsterARONIX M 5500Butanedioic acid,1-[2-[(1-oxo-2-propen-1-yl)oxy]ethyl] esterOEA 1-20Tox21_301669

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3189015
EPA DTXSID:DTXSID4044820

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HEA SUCCINATE

INCI name

HEA SUCCINATE

Description

Acryloyloxyethyl Succinate,Butanedioic acid, 1-[2-[(1-oxo-2-propen-1-yl)oxy]ethyl] ester

Record provenance

Inventory reference: 94415
Imported identity: HEA SUCCINATE
Source update: 17/08/2016

European Commission CosIng source notes

Annex records for HEA SUCCINATE

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Key data

CAS

50940-49-3

—

Restriction

—

Function

NAIL CONDITIONING: Improving and/or enhancing the cosmetic characteristics of the nail (moisturizing, increasing sheen, reducing brittleness and flaking, etc.).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11636 · HEA SUCCINATE

Ingredients with overlapping formulation functions

FUMARIC ACID/PHTHALIC ANHYDRIDE/TRICYCLODECANEDIMETHANOL COPOLYMERBINDING, COLORANT, FILM FORMING, NAIL CONDITIONING, VISCOSITY CONTROLLING

GLYCERYL DIMETHACRYLATENAIL CONDITIONING

GLYCIDOXYPROPYL TRIMETHOXYSILANENAIL CONDITIONING

GLYCOL DIMETHACRYLATENAIL CONDITIONING

HEMA TRIMELLITATE ANHYDRIDENAIL CONDITIONING

HEXANEDIOL DIMETHACRYLATENAIL CONDITIONING

HEXYL PELARGONATEHAIR CONDITIONING; NAIL CONDITIONING; DISPERSING NON-SURFACTANT; EYELASH CONDITIONING; SKIN CONDITI…

HONEY POWDERABRASIVE, BINDING, BULKING, FLAVOURING, HAIR CONDITIONING, NAIL CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HEA SUCCINATE appears in the CosIng inventory

The CosIng inventory lists HEA SUCCINATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HEA SUCCINATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HEA SUCCINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HEA SUCCINATE carries the following function designation(s):

NAIL CONDITIONING

CAS 50940-49-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for HEA SUCCINATE

This page reproduces the CosIng inventory entry for HEA SUCCINATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HEA SUCCINATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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