Is MUSCONE safe to use in EU cosmetics?

MUSCONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 10403-00-6?

CAS 10403-00-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains MUSCONE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9435118/08/2016

MUSCONE

Cyclopentadecanone, 3-methyl-, (3R)-

MUSCONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10403-00-6

CAS 10403-00-6PubChem CID 7160826

Muscone

Muscone is a cyclic ketone. — ChEBI

IUPAC name: (3R)-3-methylcyclopentadecan-1-one

Molecular formula: C16H30O
Molecular weight: 238.41 g/mol
Exact mass: 238.229665576 Da
XLogP3: 6.2
Topological polar surface area: 17.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 1

Also known as

Cyclopentadecanone, 3-methyl-, (3R)-(-)-3-MethylcyclopentadecanoneUPS3C6CV36(-)-(3R)-3-MethylcyclopentadecanoneDL-3-methylcyclopentadecanoneRefChem:926259(r)-(-)-muscone(r)-muscone

8 more reported names

(r)-3-methylcyclopentadecanone(R)-3-methylcyclopentadecan-1-oneUNII-UPS3C6CV36L-Muscone,MUSCONE [MI](3R)-3-methylcyclopentadecanoneCHEBI:167860R-(-)3-methy-cyclo pentadecanone

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:167860
ChEMBL:CHEMBL3731037
EPA DTXSID:DTXSID301365280

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match7160826

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
EMBL-EBI ChEBI	No exact record	2026-08-31
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MUSCONE

INCI name

MUSCONE

Description

Cyclopentadecanone, 3-methyl-, (3R)-

Record provenance

Inventory reference: 94351
Imported identity: MUSCONE
Source update: 18/08/2016

European Commission CosIng source notes

Annex records for MUSCONE

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Key data

CAS

10403-00-6

—

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16997 · MUSCONE

Ingredients with overlapping formulation functions

MIXED IONONESFRAGRANCE, PERFUMING

MONARDA FISTULOSA EXTRACTFLAVOURING, FRAGRANCE, PRESERVATIVE

MORINDA CITRIFOLIA OILFRAGRANCE

MUSA SAPIENTUM FLOWER WATERFRAGRANCE

MUSK KETONEFRAGRANCE, PERFUMING

MUSK XYLENEFRAGRANCE, PERFUMING

MUSKRAT MUSKFRAGRANCE, PERFUMING

MYOPORUM SANDWICENSE WOOD OILFRAGRANCE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How MUSCONE appears in the CosIng inventory

The CosIng inventory lists MUSCONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MUSCONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MUSCONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, MUSCONE carries the following function designation(s):

FRAGRANCE

CAS 10403-00-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for MUSCONE

This page reproduces the CosIng inventory entry for MUSCONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research MUSCONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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