Is ETHYLAL safe to use in EU cosmetics?

ETHYLAL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 462-95-3?

CAS 462-95-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ETHYLAL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9364429/09/2015

ETHYLAL

Diethoxymethane,Ethane, 1,1'-[methylenebis(oxy)]bis-

ETHYLAL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 462-95-3

CAS 462-95-3PubChem CID 10024

Diethoxymethane

Diethoxymethane appears as a colorless volatile liquid with an agreeable odor. Less dense than water. Vapors heavier than air. May be narcotic in high concentrations. Used as a solvent and in the manufacture of cosmetics. — CAMEO Chemicals

IUPAC name: ethoxymethoxyethane

Molecular formula: C5H12O2
Molecular weight: 104.15 g/mol
Exact mass: 104.083729621 Da
XLogP3: 0.8
Topological polar surface area: 18.5 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Diethoxy methaneEthylalFormaldehyde diethyl acetalDiethylformalMethane, diethoxy-Ethoxymethyl ethyl ether1,1-DIETHOXYMETHANE3,5-Dioxaheptene

16 more reported names

Ethane, 1,1'-[methylenebis(oxy)]bis-3,5-DioxaheptaneNSC 6754CCRIS 6891Ethane, 1,1'-(methylenebis(oxy))bis-EINECS 207-330-6UNII-56IT408V5YBRN 1697253AI3-2428656IT408V5YNSC-6754EC 207-330-64-01-00-03027 (Beilstein Handbook Reference)UN 2373ETHYLAL [INCI]RefChem:133358

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID6052112
PubMed:21375340
PubMed:17064026
PubMed:16464557
PubMed:12638751
PubMed:11349904
PubMed:11330894

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ETHYLAL

INCI name

ETHYLAL

Description

Diethoxymethane,Ethane, 1,1'-[methylenebis(oxy)]bis-

Record provenance

Inventory reference: 93644
Imported identity: ETHYLAL
Source update: 29/09/2015

European Commission CosIng source notes

Annex records for ETHYLAL

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Key data

CAS

462-95-3

207-330-6

Restriction

—

Function

SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#10140 · ETHYLAL

Ingredients with overlapping formulation functions

ETHYL PERFLUOROBUTYL ETHERSOLVENT

ETHYL PERFLUOROISOBUTYL ETHERSOLVENT

ETHYL PG-ACETAL LEVULINATESOLVENT

ETHYL PYRROLIDONESOLVENT

ETHYLENE CARBONATESOLVENT

ETHYLHEXYL ACETATEPERFUMING, SOLVENT

ETHYLHEXYL BENZOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

ETHYLHEXYL HYDROGENATED RICE BRANATESKIN CONDITIONING - EMOLLIENT; SOLVENT; SKIN CONDITIONING - OCCLUSIVE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ETHYLAL appears in the CosIng inventory

The CosIng inventory lists ETHYLAL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ETHYLAL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ETHYLAL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ETHYLAL carries the following function designation(s):

SOLVENT

CAS 462-95-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ETHYLAL

This page reproduces the CosIng inventory entry for ETHYLAL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ETHYLAL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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