Is FUCOSTEROL safe to use in EU cosmetics?

FUCOSTEROL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does FUCOSTEROL serve in cosmetics?

According to the EU CosIng inventory, FUCOSTEROL carries the following function designation(s): ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING.

What other records share CAS 17605-67-3?

CAS 17605-67-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains FUCOSTEROL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9332130/09/2015

FUCOSTEROL

Stigmasta-5,24(28)-dien-3-ol, (3\b,24E)-

FUCOSTEROL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 17605-67-3

CAS 17605-67-3PubChem CID 5281328

Fucosterol

Fucosterol is a 3beta-sterol consisting of stigmastan-3beta-ol with double bonds at positions 5 and 24(28). It has a role as an antioxidant, a metabolite and a hepatoprotective agent. It is a 3beta-hydroxy-Delta(5)-steroid, a C29-steroid, a member of phytosterols and a 3beta-sterol. It derives from a hydride of a stigmastane. — ChEBI

IUPAC name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(E,2R)-5-propan-2-ylhept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

Molecular formula: C29H48O
Molecular weight: 412.7 g/mol
Exact mass: 412.370516150 Da
XLogP3: 8.9
Topological polar surface area: 20.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 8

Also known as

Fucosterin(24E)-24-N-Propylidenecholesteroltrans-24-Ethylidenecholesterol(24E)-stigmasta-5,24(28)-dien-3beta-ol(3beta,24E)-Stigmasta-5,24(28)-dien-3-ol504ZAM710C24E-ethylidene-cholest-5-en-3beta-ol(E)-Stigmasta-5,24(28)-dien-3beta-ol

16 more reported names

CHEBI:27865Stigmasta-5,24(28)-dien-3-ol, (3beta,24E)-(3beta,24E)-stigmasta-5,24(28)-dien-olstigmasta-5,24-dien-3 beta-ol(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((E,2R)-5-propan-2-ylhept-5-en-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol24Z-ethylidenecholest-5-en-3B-olRefChem:14158924-isoethylidenecholest-5-en-3 beta-ol,delta(5)-avenasterol(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((Z,2R)-5-propan-2-ylhept-5-en-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol28-IsofucosterolStigmasta-5,24(28)-dien-3-ol, (3.beta.,24E)-Stigmasta-5,24(28)-dien-3.beta.-ol, (E)-UNII-504ZAM710C(3ss,24E)-Stigmasta-5,24(28)-dien-3-ol; trans-Stigmasta-5,24(28)dien-3ss-ol; Fucosterin24(E)-Ethylidenecholest-5-en-3.beta.-olFUCOSTEROL [MI]

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:27865
ChEMBL:CHEMBL519971
EPA DTXSID:DTXSID701033229
PubMed:27107150
PubMed:23994501

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for FUCOSTEROL

INCI name

FUCOSTEROL

Description

Stigmasta-5,24(28)-dien-3-ol, (3\b,24E)-

Record provenance

Inventory reference: 93321
Imported identity: FUCOSTEROL
Source update: 30/09/2015

European Commission CosIng source notes

Annex records for FUCOSTEROL

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Key data

CAS

17605-67-3

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#10669 · FUCOSTEROL

Ingredients with overlapping formulation functions

FRANGULA ALNUS BARK EXTRACTSKIN CONDITIONING, SKIN PROTECTING

FROG FAT EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

FRUCTOBACILLUSSKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

FRUCTOBACILLUS LYSATE EXTRACT FILTRATESKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

FUCOSYLLACTOSESKIN CONDITIONING, SKIN PROTECTING

FUCUS SERRATUS EXTRACTSKIN PROTECTING

FUSANUS ACUMINATUS SEED OILANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

GAILLARDIA ARISTATA EXTRACTBLEACHING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How FUCOSTEROL appears in the CosIng inventory

The CosIng inventory lists FUCOSTEROL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

FUCOSTEROL is also tagged with 5 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

FUCOSTEROL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, FUCOSTEROL carries the following function designation(s):

CAS 17605-67-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for FUCOSTEROL

This page reproduces the CosIng inventory entry for FUCOSTEROL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research FUCOSTEROL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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