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InventoryRef 9229718/11/2014

SALVIANOLIC ACID B

3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)

SALVIANOLIC ACID B is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 121521-90-2
CAS 121521-90-2PubChem CID 6451084

Salvianolic Acid B

Salvianolic acid B is a member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza. It has a role as an antioxidant, an antidepressant, a hypoglycemic agent, an antineoplastic agent, a hepatoprotective agent, an osteogenesis regulator, a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer, a plant metabolite, a cardioprotective agent and an autophagy inhibitor. It is a polyphenol, a member of catechols, a dicarboxylic acid, a member of 1-benzofurans and an enoate ester. ChEBI

IUPAC name
(2R)-2-[(E)-3-[(2S,3S)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoic acid
Molecular formula
C36H30O16
Molecular weight
718.6 g/mol
Exact mass
718.15338487 Da
XLogP3
4.0
Topological polar surface area
278.0 Ų
Hydrogen-bond donors
9
Hydrogen-bond acceptors
16
Covalent units
1
Defined stereocentres
4

Also known as

Lithospermic acid BDanfensuan BDan Shen Suan BMonardic acid BC1GQ844199CHEBI:134301ZINC-49538628RefChem:48698
16 more reported names
C36H30O16tanshinoate BSalBUNII-C1GQ844199Salvianolic acid B?Salvianolic acid B CRSSalvianolic acid B (Standard)HY-N1362RGLXC-19121HY-N1362SALVIANOLIC ACID B [USP-RS]SALVIANOLIC ACID B [WHO-DD]CCG-270402CS-5615EBC-457048Salvianolic acid B, >=94% (HPLC)
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match6451084

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SALVIANOLIC ACID B

INCI name

SALVIANOLIC ACID B

Description

3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)

Record provenance

Inventory reference
92297
Imported identity
SALVIANOLIC ACID B
Source update
18/11/2014
European Commission CosIng source notes

Key data

EC
Restriction
Function
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How SALVIANOLIC ACID B appears in the CosIng inventory

The CosIng inventory lists SALVIANOLIC ACID B as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SALVIANOLIC ACID B is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SALVIANOLIC ACID B is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SALVIANOLIC ACID B carries the following function designation(s):

CAS 121521-90-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for SALVIANOLIC ACID B

This page reproduces the CosIng inventory entry for SALVIANOLIC ACID B from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SALVIANOLIC ACID B and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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