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CAS 638-26-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 9202723/07/2014

10-HYDROXYSTEARIC ACID

Octadecanoic acid, 10-hydroxy-

10-HYDROXYSTEARIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 638-26-6

CAS 638-26-6PubChem CID 9561835

10-Hydroxystearic Acid

10-hydroxyoctadecanoic acid is a hydroxy fatty acid that is octadecanoic acid carrying a hydroxy group at position 10. It has a role as a bacterial xenobiotic metabolite. It is a long-chain fatty acid and a hydroxy fatty acid. It is functionally related to an octadecanoic acid. It is a conjugate acid of a 10-hydroxyoctadecanoate. — ChEBI

IUPAC name: 10-hydroxyoctadecanoic acid

Molecular formula: C18H36O3
Molecular weight: 300.5 g/mol
Exact mass: 300.26644501 Da
XLogP3: 6.5
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Octadecanoic acid, 10-hydroxy-10-hydroxy-octadecanoic acid384M5B7IFLNSC-79060CHEBI:143095RefChem:437036Rosilic acidC18H36O3

16 more reported names

UNII-384M5B7IFL10-hydroxy stearic acidAI3-26309(R)-10-hydroxystearicaciDL-10-hydroxy stearic acidUSDA 10-hydroxystearic acidxi-10-Hydroxyoctadecanoic acid10-HYDROXYOCTADECANOICACIDDL-10-HYDROXYSTEARIC ACID10-Hydroxystearic Acid, 10-HSANSC 79060STEARIC ACID, .IOTA.-HYDROXY-DL-10-hydroxy stearic acid; 10-HODAAS-5896910-HYDROXYSTEARIC ACID, (+/-)-CS-0186310

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:143095
EPA DTXSID:DTXSID901314578
PubMed:22261174
PubMed:22189865
PubMed:21943732
PubMed:21720824
PubMed:21450085
PubMed:21329502
PubMed:21207107
PubMed:19818319
PubMed:18296335
PubMed:17644293
PubMed:17485848
PubMed:15556558

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 10-HYDROXYSTEARIC ACID

INCI name

10-HYDROXYSTEARIC ACID

Description

Octadecanoic acid, 10-hydroxy-

Record provenance

Inventory reference: 92027
Imported identity: 10-HYDROXYSTEARIC ACID
Source update: 23/07/2014

European Commission CosIng source notes

Annex records for 10-HYDROXYSTEARIC ACID

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Key data

CAS

638-26-6

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Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#126 · 10-HYDROXYSTEARIC ACID

Ingredients with overlapping formulation functions

(CODONOPSIS TANGSHEN/DIOSCOREA JAPONICA) ROOT/ATRACTYLODES JAPONICA RHIZOME/POR…HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

(LAVANDULA ANGUSTIFOLIA/MELISSA OFFICINALIS/HYPERICUM PERFORATUM) FLOWER/(CAMEL…ANTI-SEBUM, ANTIMICROBIAL, SKIN CONDITIONING, SKIN PROTECTING

(LEPIDIUM MEYENII/SARCODON ASPRATUS) ROOT WATERANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

(RH-POLYPEPTIDE-111 RH-POLYPEPTIDE-94 RH-POLYPEPTIDE-95) DIMERHAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

16-ALPHA ETHYL ESTRADIOLCARBOXYLATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

16-BETA METHYL ESTRADIOLPROPANOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

2,5-DIHYDROXYBENZOYL DIPEPTIDE-27HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

2,5-DIHYDROXYBENZOYL DIPEPTIDE-48HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 10-HYDROXYSTEARIC ACID appears in the CosIng inventory

The CosIng inventory lists 10-HYDROXYSTEARIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

10-HYDROXYSTEARIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

10-HYDROXYSTEARIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 10-HYDROXYSTEARIC ACID carries the following function designation(s):

CAS 638-26-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 10-HYDROXYSTEARIC ACID

This page reproduces the CosIng inventory entry for 10-HYDROXYSTEARIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 10-HYDROXYSTEARIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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