Is SCHISANDRIN safe to use in EU cosmetics?

SCHISANDRIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 7432-28-2?

CAS 7432-28-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SCHISANDRIN?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9194219/11/2014

SCHISANDRIN

SCHISANDRIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7432-28-2

CAS 7432-28-2PubChem CID 3001664

Schisandrin

Schisandrin has been reported in Schisandra sphenanthera, Schisandra rubriflora, and other organisms with data available. — LOTUS - the natural products occurrence database

IUPAC name: (9S,10S)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol

Molecular formula: C24H32O7
Molecular weight: 432.5 g/mol
Exact mass: 432.21480336 Da
XLogP3: 4.0
Topological polar surface area: 75.6 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 2

Also known as

SchizandrinWuweizichun AWuweizi alcohol ASchizandrol AG01BQC0879Dibenzo(a,c)cycloocten-6-ol, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer(9S,10S)-3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo(10.4.0.02,7)hexadeca-1(16),2,4,6,12,14-hexaen-9-olRefChem:47480

16 more reported names

694-563-53,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo(10.4.0.02,7)hexadeca-1(16),2,4,6,12,14-hexaen-9-olwuweizisu ASchizandrol(+)-Schizandrin(6S,7S)-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-6-ol(6S,7S,12aR)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-6-olSchisandrinehexamethoxy(dimethyl)[?]olGomisinsWuweizinsOmijaC24H32O7Magnolia VineSchisandrin CRS(+)-schisandrin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL253688
PubMed:17190445
PubMed:9313872

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SCHISANDRIN

INCI name

SCHISANDRIN

Record provenance

Inventory reference: 91942
Imported identity: SCHISANDRIN
Source update: 19/11/2014

European Commission CosIng source notes

Annex records for SCHISANDRIN

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Key data

CAS

7432-28-2

—

Restriction

—

Function

BLEACHING: Bleaching or lightening the shade of hair and/or skin.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#25396 · SCHISANDRIN

Ingredients with overlapping formulation functions

SACCHAROMYCES/LAVENDER FLOWER/LEAF/STEM EXTRACT FERMENT FILTRATEANTI-SEBUM, ANTIOXIDANT, BLEACHING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLL…

SACCHAROMYCES/VACCINIUM VITIS-IDAEA FRUIT FERMENT EXTRACTBLEACHING, SKIN CONDITIONING

SALIX BLINII LEAF EXTRACTANTIOXIDANT, BLEACHING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

SAURURUS CHINENSIS ROOT EXTRACTBLEACHING

SEA CUCUMBER SECRETION EXTRACTASTRINGENT; BLEACHING; SKIN PROTECTING; EXFOLIATING; SKIN CONDITIONING - MISCELLANEOUS

SELENICEREUS MONACANTHUS BUD EXTRACTANTIOXIDANT, BLEACHING, SKIN CONDITIONING, SKIN PROTECTING

SH-DECAPEPTIDE-3BLEACHING, SKIN PROTECTING

SH-DECAPEPTIDE-3 AMIDEBLEACHING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SCHISANDRIN appears in the CosIng inventory

The CosIng inventory lists SCHISANDRIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SCHISANDRIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SCHISANDRIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SCHISANDRIN carries the following function designation(s):

BLEACHING

CAS 7432-28-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SCHISANDRIN

This page reproduces the CosIng inventory entry for SCHISANDRIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SCHISANDRIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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