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InventoryRef 9188123/07/2014

AVENANTHRAMIDES

Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-,Benzoic acid, 5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxy…

AVENANTHRAMIDES is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 108605-69-2
CAS 108605-69-2PubChem CID 10087955

Avenanthramide B

Avenanthramide B is a monohydroxybenzoic acid resulting from the formal condensation of the carboxy group of ferulic acid with the amino group of 2-amino-5-hydroxybenzoic acid. It is an oat phytoalexin produced in response to pathogen attack and elicitation. It has a role as a phytoalexin, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a member of cinnamamides, a monomethoxybenzene, a monohydroxybenzoic acid, a member of phenols and an amidobenzoic acid. It is functionally related to a trans-ferulic acid. It is a conjugate acid of an avenanthramide B(1-). ChEBI

IUPAC name
5-hydroxy-2-[[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]amino]benzoic acid
Molecular formula
C17H15NO6
Molecular weight
329.30 g/mol
Exact mass
329.08993720 Da
XLogP3
2.5
Topological polar surface area
116.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Avenanthramide 1Avenanthramide 2FAvenanthramide BFF8BQ5730ILN-feruloyl-5-hydroxyanthranilic acidBenzoic acid, 5-hydroxy-2-(((2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl)amino)-CHEBI:167489Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
14 more reported names
N-(4'-hydroxy-3'-methoxy-(E)-cinnamoyl)-5-hydroxyanthranilic acidN-[4'-hydroxy-3'-methoxy-(E)-cinnamoyl]-5-hydroxyanthranilic acid5-hydroxy-2-(((E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl)amino)benzoic acidRefChem:560398UNII-F8BQ5730IL(Z)-N-Feruloyl-5-hydroxyanthranilic acid5-hydroxy-2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamido]benzoic acid5-Hydroxy-2-(((2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoyl)amino)benzoic acid(E)-5-Hydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)acrylamido)benzoic acidAvenanthramide B, analytical standardTN8487N-(4'-hydroxy-3'methoxy-(e)-cinnamoyl)-5-hydroxyanthranilic acid5-hydroxy-2-{[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]amino}benzoic acid5-hydroxy-2-{[(2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]amino}benzoic acid
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match10087955

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 108605-70-5
CAS 108605-70-5PubChem CID 5281157

Avenanthramide A

Avenanthramide A is a hydroxycinnamic acid. It is a conjugate acid of an avenanthramide A(1-). ChEBI

IUPAC name
5-hydroxy-2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]benzoic acid
Molecular formula
C16H13NO5
Molecular weight
299.28 g/mol
Exact mass
299.07937252 Da
XLogP3
2.6
Topological polar surface area
107.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

Avenanthramide 2PAvenanthramide BPG1I8LE060CBenzoic acid, 5-hydroxy-2-(((2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl)amino)-Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-2-(((E)-3-(4-hydroxyphenyl)prop-2-enoyl)amino)benzoic acidRefChem:560397UNII-G1I8LE060C
15 more reported names
(E)-5-Hydroxy-2-(3-(4-hydroxyphenyl)acrylamido)benzoic acid(Z)-N-Coumaroyl-5-hydroxyanthranilic acidAvenalumin I5-Hydroxy-2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]benzoic Acid; Avenanthramide 2p; Avenanthramide BpCHEBI:29395-hydroxy-2-[3-(4-hydroxyphenyl)prop-2-enamido]benzoic acid5-hydroxy-2-[(2E)-3-(4-hydroxyphenyl)prop-2-enamido]benzoic acidAvenanthramide A, analytical standardEBC-618313HY-114977CS-00647225-Hydroxy-N-(4-hydroxycinnamoyl)anthranilic acidN-(4'-hydroxy-(e)-cinnamoyl)-5-hydroxyanthranilic acid5-Hydroxy-2-[(2E)-3-(4-hydroxyphenyl)prop-2-enamido]benzoate5-hydroxy-2-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]amino}benzoic acid
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match5281157

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 116764-15-9
CAS 116764-15-9PubChem CID 11723200

Avenanthramide C

2-{[(2E)-3-(3,4-dihydroxyphenyl)-1-hydroxyprop-2-en-1-ylidene]amino}-5-hydroxybenzoic acid is an alkaloid and a member of benzamides. ChEBI

IUPAC name
2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoic acid
Molecular formula
C16H13NO6
Molecular weight
315.28 g/mol
Exact mass
315.07428713 Da
XLogP3
2.1
Topological polar surface area
127.0 Ų
Hydrogen-bond donors
5
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Avenanthramide BCBenzoic acid, 2-(((2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl)amino)-5-hydroxy-2-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enamido]-5-hydroxybenzoic acid2-(((E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl)amino)-5-hydroxybenzoic acid2-((2E)-3-(3,4-dihydroxyphenyl)prop-2-enamido)-5-hydroxybenzoic acidRefChem:560399Avenanthramide 2CAvenanthramide
16 more reported names
5FRF61BOYU(E)-2-(3-(3,4-Dihydroxyphenyl)acrylamido)-5-hydroxybenzoic acid2-[3-(3,4-DIHYDROXYPHENYL)PROP-2-ENAMIDO]-5-HYDROXYBENZOIC ACIDN-(3',4'-dihydroxycinnamoyl)-5-hydroxyanthranilic acidUNII-5FRF61BOYUAvenanthramide-c2-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxybenzoic Acid; Avenanthramide 2c; Avenanthramide BcCHEBI:185306Avenanthramide C, analytical standardTN83222-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxy-benzoic AcidCS-0086258N-(3,4-Dihydroxycinnamoyl)-5-hydroxyanthranilic acidN-(3,4-dihydroxy)-(e)-cinnamoyl-5-hydroxyanthranilic acid2-[(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enamido]-5-hydroxybenzoate2-{[(2E)-3-(3,4-dihydroxyphenyl)-1-hydroxyprop-2-en-1-ylidene]amino}-5-hydroxybenzoic acid
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match11723200

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 172549-38-1
CAS 172549-38-1PubChem CID 101688490

5-Hydroxy-2-(((2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl)amino)benzoic acid

Avenanthramide L is an amidobenzoic acid. ChEBI

IUPAC name
5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)penta-2,4-dienoyl]amino]benzoic acid
Molecular formula
C18H15NO5
Molecular weight
325.3 g/mol
Exact mass
325.09502258 Da
XLogP3
3.2
Topological polar surface area
107.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

5-Hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl]amino]benzoic acidRefChem:1072971Avenanthramide L5-Hydroxy-2-{[(2E,4E)-5-(4-hydroxyphenyl)penta-2,4-dienoyl]amino}benzoic acidCHEBI:175146
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for AVENANTHRAMIDES

INCI name

AVENANTHRAMIDES

Description

Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-,Benzoic acid, 5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-

Record provenance

Inventory reference
91881
Imported identity
AVENANTHRAMIDES
Source update
23/07/2014
European Commission CosIng source notes

Key data

CAS
108605-69-2,108605-70-5,116764-15-9,172549-38-1
EC
Restriction
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How AVENANTHRAMIDES appears in the CosIng inventory

The CosIng inventory lists AVENANTHRAMIDES as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

AVENANTHRAMIDES is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

AVENANTHRAMIDES is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, AVENANTHRAMIDES carries the following function designation(s):

CAS 108605-69-2,108605-70-5,116764-15-9,172549-38-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for AVENANTHRAMIDES

This page reproduces the CosIng inventory entry for AVENANTHRAMIDES from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research AVENANTHRAMIDES and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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