AVENANTHRAMIDES
Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-,Benzoic acid, 5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxy…
AVENANTHRAMIDES is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties

Avenanthramide B
Avenanthramide B is a monohydroxybenzoic acid resulting from the formal condensation of the carboxy group of ferulic acid with the amino group of 2-amino-5-hydroxybenzoic acid. It is an oat phytoalexin produced in response to pathogen attack and elicitation. It has a role as a phytoalexin, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a member of cinnamamides, a monomethoxybenzene, a monohydroxybenzoic acid, a member of phenols and an amidobenzoic acid. It is functionally related to a trans-ferulic acid. It is a conjugate acid of an avenanthramide B(1-). — ChEBI
- IUPAC name
- 5-hydroxy-2-[[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]amino]benzoic acid
- Molecular formula
- C17H15NO6
- Molecular weight
- 329.30 g/mol
- Exact mass
- 329.08993720 Da
- XLogP3
- 2.5
- Topological polar surface area
- 116.0 Ų
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
14 more reported names
External database identifiers
- ChEBI:CHEBI:167489
- EPA DTXSID:DTXSID50148603
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Melting Point: 246 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Avenanthramide A
Avenanthramide A is a hydroxycinnamic acid. It is a conjugate acid of an avenanthramide A(1-). — ChEBI
- IUPAC name
- 5-hydroxy-2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]benzoic acid
- Molecular formula
- C16H13NO5
- Molecular weight
- 299.28 g/mol
- Exact mass
- 299.07937252 Da
- XLogP3
- 2.6
- Topological polar surface area
- 107.0 Ų
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
15 more reported names
External database identifiers
- ChEBI:CHEBI:2939
- EPA DTXSID:DTXSID801316626
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Melting Point: 277 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Avenanthramide C
2-{[(2E)-3-(3,4-dihydroxyphenyl)-1-hydroxyprop-2-en-1-ylidene]amino}-5-hydroxybenzoic acid is an alkaloid and a member of benzamides. — ChEBI
- IUPAC name
- 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoic acid
- Molecular formula
- C16H13NO6
- Molecular weight
- 315.28 g/mol
- Exact mass
- 315.07428713 Da
- XLogP3
- 2.1
- Topological polar surface area
- 127.0 Ų
- Hydrogen-bond donors
- 5
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:185306
- EPA DTXSID:DTXSID60151507
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

5-Hydroxy-2-(((2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl)amino)benzoic acid
Avenanthramide L is an amidobenzoic acid. — ChEBI
- IUPAC name
- 5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)penta-2,4-dienoyl]amino]benzoic acid
- Molecular formula
- C18H15NO5
- Molecular weight
- 325.3 g/mol
- Exact mass
- 325.09502258 Da
- XLogP3
- 3.2
- Topological polar surface area
- 107.0 Ų
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
External database identifiers
- ChEBI:CHEBI:175146
- EPA DTXSID:DTXSID401127813
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for AVENANTHRAMIDES
INCI name
AVENANTHRAMIDES
Description
Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-,Benzoic acid, 5-hydroxy-2-[[(2E,4E)-5-(4-hydroxyphenyl)-1-oxo-2,4-pentadien-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-,Benzoic acid, 5-hydroxy-2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-
Record provenance
- Inventory reference
- 91881
- Imported identity
- AVENANTHRAMIDES
- Source update
- 23/07/2014
Annex records for AVENANTHRAMIDES
Key data
- ANTIOXIDANT
- Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- SKIN PROTECTING
- Helping to avoid harmful effects to the skin from external factors.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How AVENANTHRAMIDES appears in the CosIng inventory
The CosIng inventory lists AVENANTHRAMIDES as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
AVENANTHRAMIDES is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for AVENANTHRAMIDES
This page reproduces the CosIng inventory entry for AVENANTHRAMIDES from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research AVENANTHRAMIDES and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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