Skip to main content
InventoryRef 9160728/10/2014

NATAMYCIN

6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,2…

NATAMYCIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 7681-93-8
CAS 7681-93-8PubChem CID 5284447

Natamycin

Natamycin is a Polyene Antimicrobial. FDA Pharm Classes

IUPAC name
(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
Molecular formula
C33H47NO13
Molecular weight
665.7 g/mol
Exact mass
665.30474055 Da
XLogP3
-1.3
Topological polar surface area
231.0 Ų
Hydrogen-bond donors
7
Hydrogen-bond acceptors
14
Covalent units
1
Defined stereocentres
14

Also known as

pimaricinMyprozinePimafucinTennecetinNatacynNatamicinaNatamycineDelvocid
16 more reported names
MycophytPimaracinSynogilNatamycinumPimarizinAntibiotic A-5283DelvolanPimaricineCL 12,6258O0C852CPOINS NO.235INS-235NSC-759167CL 12625CL-12625E-235
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for NATAMYCIN

INCI name

NATAMYCIN

Description

6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-

Record provenance

Inventory reference
91607
Imported identity
NATAMYCIN
Source update
28/10/2014
European Commission CosIng source notes

Key data

EC
231-683-5 (I)
Restriction
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How NATAMYCIN appears in the CosIng inventory

The CosIng inventory lists NATAMYCIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NATAMYCIN is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NATAMYCIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, NATAMYCIN carries the following function designation(s):

CAS 7681-93-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for NATAMYCIN

This page reproduces the CosIng inventory entry for NATAMYCIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research NATAMYCIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

Check your formula

Scan a full INCI list to detect NATAMYCIN and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to NATAMYCIN, its identifiers or nearby name variants.

Search