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InventoryRef 9039512/09/2018

HYDROXYTYROSOL

1,2-Benzenediol, 4-(2-hydroxyethyl)-

HYDROXYTYROSOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10597-60-1
CAS 10597-60-1PubChem CID 82755

Hydroxytyrosol

Hydroxytyrosol is a member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities. It has a role as an antioxidant, a metabolite and an antineoplastic agent. It is a primary alcohol and a member of catechols. It is functionally related to a 2-(4-hydroxyphenyl)ethanol. — ChEBI

IUPAC name
4-(2-hydroxyethyl)benzene-1,2-diol
Molecular formula
C8H10O3
Molecular weight
154.16 g/mol
Exact mass
154.062994177 Da
XLogP3
-0.7
Topological polar surface area
60.7 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

3,4-Dihydroxyphenylethanol2-(3,4-Dihydroxyphenyl)ethanol4-(2-hydroxyethyl)-1,2-BenzenediolHomoprotocatechuyl alcoholQEU0NE4O90CHEBI:68889RefChem:7895763,4-DHPEA
16 more reported names
600-704-34-(3-hydroxypropyl)benzene-1,2-dioldopet3,4-Dihydroxyphenethyl Alcohol3-Hydroxytyrosol3,4-Dihydroxyphenethylalcohol1,2-Benzenediol, 4-(2-hydroxyethyl)-beta-3,4-Dihydroxyphenylethyl alcohol3,4-Dihydroxyphenyl ethanol3,4-dihydroxy-1-benzeneethanolhydroxy tyrosolHydroxy Tyrosol (>85%)HY-N05702-(3,4-Dihydroxyphenyl)ethyl AlcoholHydroxy Tyrosol-d3UNII-QEU0NE4O90
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:68889

hydroxytyrosol

A member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities.

Formula
C8H10O3
Average mass
154.165 g/mol
Monoisotopic mass
154.06299 Da
Formal charge
0
  • catechols — is a (CHEBI:33566)
  • primary alcohol — is a (CHEBI:15734)
  • metabolite — has role (CHEBI:25212)
  • antioxidant — has role (CHEBI:22586)
  • antineoplastic agent — has role (CHEBI:35610)
  • 2-(4-hydroxyphenyl)ethanol — has functional parent (CHEBI:1879)
  • metabolite — has role (CHEBI:25212)
  • antioxidant — has role (CHEBI:22586)
  • antineoplastic agent — has role (CHEBI:35610)
  • catechols — is a (CHEBI:33566)
  • primary alcohol — is a (CHEBI:15734)
Additional curated names
4-(2-hydroxyethyl)benzene-1,2-diol3,4-dihydroxyphenylethanoldopetHomoprotocatechuyl alcoholHydroxytyrosol
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2016-08-15. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match82755

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (89.8%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (91.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (83.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 49 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDROXYTYROSOL

INCI name

HYDROXYTYROSOL

Description

1,2-Benzenediol, 4-(2-hydroxyethyl)-

Record provenance

Inventory reference
90395
Imported identity
HYDROXYTYROSOL
Source update
12/09/2018
European Commission CosIng source notes
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Key data

CAS
10597-60-1
EC
—
Restriction
—
Function
BLEACHING
Bleaching or lightening the shade of hair and/or skin.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13426 · HYDROXYTYROSOL

Ingredients with overlapping formulation functions

HYDROLYZED XANTHOMONAS CAMPESTRIS POLYSACCHARIDEBLEACHING
HYDROXYDODECYL DIMETHOXYBENZAMIDEBLEACHING, SKIN PROTECTING
HYDROXYPHENYL PROPIONAMIDEANTIOXIDANT, ASTRINGENT, BLEACHING, SKIN CONDITIONING, SKIN PROTECTING
HYDROXYRESVERATROLBLEACHING, SKIN CONDITIONING, SKIN PROTECTING
HYPOXIS AUREA ROOT EXTRACTBLEACHING, SKIN CONDITIONING
ICARISIDE IIANTIOXIDANT, BLEACHING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING
ISOBUTYLAMIDO THIAZOLYL RESORCINOLBLEACHING
ISODON INFLEXUS BRANCH/LEAF EXTRACTBLEACHING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How HYDROXYTYROSOL appears in the CosIng inventory

The CosIng inventory lists HYDROXYTYROSOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDROXYTYROSOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDROXYTYROSOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HYDROXYTYROSOL carries the following function designation(s):

CAS 10597-60-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for HYDROXYTYROSOL

This page reproduces the CosIng inventory entry for HYDROXYTYROSOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HYDROXYTYROSOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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