InventoryRef 9006617/03/2014
SEC-BUTYL ACETATE
Acetic acid, 1-methylpropyl ester
SEC-BUTYL ACETATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
CAS 105-46-4PubChem CID 7758
Sec-Butyl acetate
Watery colorless liquid with a pleasant, fruity odor. Floats on water. Produces irritating vapor. (USCG, 1999) — CAMEO Chemicals
- IUPAC name
- butan-2-yl acetate
- Molecular formula
- C6H12O2
- Molecular weight
- 116.16 g/mol
- Exact mass
- 116.083729621 Da
- XLogP3
- 1.7
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
dl-sec-Butyl acetate2-Butyl acetate1-Methylpropyl acetateAcetic acid, 1-methylpropyl estersec-Butyl ethanoate1-Methylpropyl ethanoateAcetic acid, sec-butyl esterAcetic acid secondary butyl ester
16 more reported names
NSC 8034HSDB 673UNII-UVH2QII6CGUVH2QII6CGEINECS 203-300-1BRN 17206892-ACETOXYBUTANENSC-8034UN1123CH3COOCH(CH3)C2H5SEC-BUTYL ACETATE [MI]4-02-00-00148 (Beilstein Handbook Reference)1-METHYLPROPYL ETHANOATE [HSDB]SEC-BUTYL ACETATE DL-FORM [MI]secbutyl acetate2butyl acetate
External database identifiers
- EPA DTXSID:DTXSID0047612
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match7758
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 234 °F at 760 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Boiling Point: 112 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 112 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 234 °F Source: Occupational Safety and Health Administration (OSHA)
- Boiling Point: 112 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Boiling Point: 234 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Color/Form: Colorless liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.872 at 68 °F (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
- Density: 0.8748 g/cu cm at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 0.87 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 0.872 Source: Occupational Safety and Health Administration (OSHA)
- Density: 0.862-0.866 @ 20°C Source: PAC Chemical Database, U.S. Department of Energy
- Density: 0.86 Source: The National Institute for Occupational Safety and Health (NIOSH)
- Flash Point: 62 °F (USCG, 1999) Source: CAMEO Chemicals
- Flash Point: 31 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 31 °C (88 °F) (open cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 62 °F (closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 17 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 62 °F Source: Occupational Safety and Health Administration (OSHA)
- Flash Point: 62 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- LogP: log Kow = 1.72 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 1.51 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -100 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: -98.9 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -99 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -100 °F Source: Occupational Safety and Health Administration (OSHA)
- Melting Point: -98.9 °C Source: PAC Chemical Database, U.S. Department of Energy
- Melting Point: -100 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Odor: HAS FRUITY ODOR CHARACTERISTIC OF ACETATE ESTERS Source: Hazardous Substances Data Bank (HSDB)
- Odor: Pleasant fruity odor Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Watery colorless liquid with a pleasant, fruity odor. Floats on water. Produces irritating vapor. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: Colorless liquid with a pleasant, fruity odor; [NIOSH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: Colorless liquid with a pleasant, fruity odor. Source: Occupational Safety and Health Administration (OSHA)
- Physical Description: Colorless liquid with a pleasant, fruity odor. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Refractive Index: Index of refraction: 1.3888 at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.8 % (NIOSH, 2024) Source: CAMEO Chemicals
- Solubility: Miscible with alcohol and ether Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble ethanol, ethyl ether; slightly soluble in carbon tetrachloride Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 6200 mg/L at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water, g/100ml at 20 °C: 0.8 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: 0.8% Source: The National Institute for Occupational Safety and Health (NIOSH)
- Vapor Pressure: 51.7 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Vapor Pressure: 17.0 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 17 mm Hg at 20 °C /ext/ Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, kPa at 20 °C: 1.33 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 10 mmHg Source: Occupational Safety and Health Administration (OSHA)
- Vapor Pressure: 17 [mm Hg] @20 °C Source: PAC Chemical Database, U.S. Department of Energy
- Vapor Pressure: 10 mmHg Source: The National Institute for Occupational Safety and Health (NIOSH)
- Exposure Routes: The substance can be absorbed into the body by inhalation of its vapour. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: inhalation, ingestion, skin and/or eye contact Source: The National Institute for Occupational Safety and Health (NIOSH)
- First Aid: Excerpt from NIOSH Pocket Guide for sec-Butyl acetate:; Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: WATER FLUSH PROMPTLY - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.; Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024) Source: CAMEO Chemicals
- ERG2024, Guide 129 (Butyl acetates): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
- First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush promptly - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Note: This chemical does not meet GHS hazard criteria for 4.9% (16 of 325) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H225 (94.8%): Highly Flammable liquid and vapor [Danger Flammable liquids] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 325 reports by companies from 10 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 16 of 325 reports by companies.; There are 9 notifications provided by 309 of 325 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: NITE-CMC
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H303: May be harmful if swallowed [Warning Acute toxicity, oral]; H316: Causes mild skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] Source: NITE-CMC
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Target Organs: Eyes, skin, respiratory system, central nervous system Source: The National Institute for Occupational Safety and Health (NIOSH)
- Environmental Bioconcentration: An estimated BCF of 6 was calculated in fish for sec-butyl acetate(SRC), using a log Kow of 1.72(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 16(SRC), determined from a structure estimation method(2), indicates that sec-butyl acetate is expected to have very high mobility in soil(SRC). Volatilization of sec-butyl acetate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.2X10-4 atm-cu m/mole(SRC), based upon its vapor pressure, 17 mm Hg(3), and water solubility, 6200 mg/L(4). sec-Butyl acetate is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). A value of 86% of theoretical BOD using activated sludge in the Japanese MITI test(5) suggests that biodegradation is an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 16(SRC), determined from a structure estimation method(2), indicates that sec-butyl acetate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 4.2X10-4 atm-cu m/mole(SRC), derived from its vapor pressure, 17 mm Hg(4), and water solubility, 6200 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 5.4 hours and 5 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 6(SRC), from its log Kow of 1.72(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). A value of 86% of theoretical BOD using activated sludge in the Japanese MITI test(9) suggests that biodegradation is an important environmental fate process in water(SRC). Hydrolysis is expected to occur slowly based upon estimated hydrolysis half-lives of 3.5 years and 128 days at pH 7 and 8, respectively(10). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), sec-butyl acetate, which has a vapor pressure of 17 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase sec-butyl acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 70 hours(SRC), calculated from its rate constant of 5.5X10-12 cu cm/molecule-sec at 25 °C(3). sec-Butyl acetate does not contain chromophores that absorb at wavelengths >290 nm(4) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Sources/Uses: Used as a solvent (nitrocellulose lacquers, thinners, nail enamels, leather finishes); [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Pulp and Paper Processing [Category: Industry]; Painting (Solvents) [Category: Paint]; Leather Tanning and Processing [Category: Industry]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Solvent for nitrocellulose lacquers, thinners, nail enamels, leather finishes Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | No exact record | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for SEC-BUTYL ACETATE
INCI name
SEC-BUTYL ACETATE
Description
Acetic acid, 1-methylpropyl ester
Record provenance
- Inventory reference
- 90066
- Imported identity
- SEC-BUTYL ACETATE
- Source update
- 17/03/2014
Annex records for SEC-BUTYL ACETATE
Key data
CAS
EC
Restriction
—
Function
- SKIN CONDITIONING
- Maintaining the skin in good condition.
- SOLVENT
- Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal
How SEC-BUTYL ACETATE appears in the CosIng inventory
The CosIng inventory lists SEC-BUTYL ACETATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
SEC-BUTYL ACETATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
SEC-BUTYL ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.
According to the EU CosIng inventory, SEC-BUTYL ACETATE carries the following function designation(s):
CAS 105-46-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Source note for SEC-BUTYL ACETATE
This page reproduces the CosIng inventory entry for SEC-BUTYL ACETATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research SEC-BUTYL ACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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