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CAS 355-04-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8943022/10/2012

PERFLUOROISOHEXANE

Pentane, 1,1,1,2,2,3,3,4,5,5,5-undecafluoro-4-(trifluoromethyl)-

PERFLUOROISOHEXANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 355-04-4

CAS 355-04-4PubChem CID 67726

Perfluoroisohexane

IUPAC name: 1,1,1,2,2,3,3,4,5,5,5-undecafluoro-4-(trifluoromethyl)pentane

Molecular formula: C6F14
Molecular weight: 338.04 g/mol
Exact mass: 337.9776443 Da
XLogP3: 5.1
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 14
Covalent units: 1
Defined stereocentres: 0

Also known as

Perfluoro(2-methylpentane)Tetradecafluoro-2-methylpentaneEINECS 206-575-62-PerfluoromethylpentaneUNII-698P33664YFLUTEC PC-1698P33664YEC 206-575-6

11 more reported names

UNDECAFLUORO-2-(TRIFLUOROMETHYL)PENTANERefChem:171664PERFLUOROISOHEXANE [INCI]ROVMKEZVKFJNBD-UHFFFAOYSA-NPerfluoro-2-methylpentanePentane, 1,1,1,2,2,3,3,4,5,5,5-undecafluoro-4-(trifluoromethyl)-Pentane, undecafluoro-2-(trifluoromethyl)-perfluoro-2-methyl-pentaneTetradecafluoro-2-methyl pentaneAS-868801,1,1,2,2,3,3,4,5,5,5-Undecafluoro-4-(trifluoromethyl)pentane #

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID40188992

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PERFLUOROISOHEXANE

INCI name

PERFLUOROISOHEXANE

Description

Pentane, 1,1,1,2,2,3,3,4,5,5,5-undecafluoro-4-(trifluoromethyl)-

Record provenance

Inventory reference: 89430
Imported identity: PERFLUOROISOHEXANE
Source update: 22/10/2012

European Commission CosIng source notes

Annex records for PERFLUOROISOHEXANE

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Key data

CAS

355-04-4

206-575-6

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#20474 · PERFLUOROISOHEXANE

Ingredients with overlapping formulation functions

PENTYLNONANESKIN CONDITIONING - EMOLLIENT

PENTYLPHENYL PENTYLBENZOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PERFLUOROBUTYLETHYL STEARYL DIMETHICONEANTIFOAMING; SKIN CONDITIONING - EMOLLIENT; HAIR CONDITIONING; DISPERSING NON-SURFACTANT; SLIP MODI…

PERFLUOROCAPRYLYL TRIETHOXYSILYLETHYL METHICONEBINDING, SKIN CONDITIONING - EMOLLIENT

PERFLUORONONYLETHYL PEG-8 PHENYLISOPROPYL DIMETHCONESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PERFLUORONONYLETHYL PEG-8 PHENYLISOPROPYL DIMETHICONESKIN CONDITIONING - EMOLLIENT

PERFLUOROOCTYLETHYL/DIPHENYL DIMETHICONE COPOLYMERSKIN CONDITIONING - EMOLLIENT

PERILLA FRUTESCENS SEED OILSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PERFLUOROISOHEXANE appears in the CosIng inventory

The CosIng inventory lists PERFLUOROISOHEXANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PERFLUOROISOHEXANE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PERFLUOROISOHEXANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PERFLUOROISOHEXANE carries the following function designation(s):

CAS 355-04-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PERFLUOROISOHEXANE

This page reproduces the CosIng inventory entry for PERFLUOROISOHEXANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PERFLUOROISOHEXANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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