Is LACTIDE safe to use in EU cosmetics?

LACTIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 95-96-5?

CAS 95-96-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LACTIDE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8942619/10/2012

LACTIDE

1,4-Dioxane-2,5-dione, 3,6-dimethyl-

LACTIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 95-96-5

CAS 95-96-5PubChem CID 7272

Lactide

Lactide is a member of dioxanes. — ChEBI

IUPAC name: 3,6-dimethyl-1,4-dioxane-2,5-dione

Molecular formula: C6H8O4
Molecular weight: 144.12 g/mol
Exact mass: 144.04225873 Da
XLogP3: 0.6
Topological polar surface area: 52.6 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Dilactidep-Dioxane-2,5-dione, 3,6-dimethyl-RefChem:57699202-468-3DL-LactideDL-Dilactide1,4-Dioxane-2,5-dione, 3,6-dimethyl-3,6-Dimethyl-2,5-dioxo-1,4-dioxane

16 more reported names

Lactic acid, bimol. cyclic ester7EH08MWO6MPropanoic acid, 2-hydroxy-, bimol. cyclic esterAI3-05059LACTIDE, DL-NSC-403080p-Dioxane-2, 3,6-dimethyl-Purasorb DL; dl-Dilactide; rac-LactideAS-17933L-Lactide homopolymer2,5-DIMETHYL-3,6-DIOXO-1,4-DIOXANEResomer R208EINECS 202-468-3UNII-7EH08MWO6MNSC 403080lactid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:177651
ChEMBL:CHEMBL3185272
EPA DTXSID:DTXSID7041253
PubMed:23030249
PubMed:23016983
PubMed:23009063
PubMed:22968601
PubMed:22961054
PubMed:22942005
PubMed:22930321
PubMed:22903466
PubMed:22892614
PubMed:22881441
PubMed:22791551
PubMed:22765928

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LACTIDE

INCI name

LACTIDE

Description

1,4-Dioxane-2,5-dione, 3,6-dimethyl-

Record provenance

Inventory reference: 89426
Imported identity: LACTIDE
Source update: 19/10/2012

European Commission CosIng source notes

Annex records for LACTIDE

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Key data

CAS

95-96-5

202-468-3

Restriction

—

Function

ABRASIVE: Removing unwanted tissue or foreign materials from various body surfaces, including mechanical tooth cleaning and/or gloss improvement.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#14275 · LACTIDE

Ingredients with overlapping formulation functions

KAOLINABRASIVE, ABSORBENT, ANTICAKING, BULKING, COLORANT, OPACIFYING

KIWI FRUIT EXTRACT BETA-GLUCANABRASIVE, ANTI-SEBORRHEIC, SKIN CONDITIONING

KOCHIA SCOPARIA FRUIT POWDERABRASIVE, SKIN PROTECTING

KURUMI KAKUABRASIVE

LACTOBACILLUS/PAPAYA FRUIT FERMENT EXTRACTABRASIVE, HAIR CONDITIONING, SKIN CONDITIONING

LAPIS LAZULIABRASIVE

LAURYL ACRYLATE/VA CROSSPOLYMERABRASIVE

LEONURUS ARTEMISIA POWDERABRASIVE, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LACTIDE appears in the CosIng inventory

The CosIng inventory lists LACTIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LACTIDE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LACTIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LACTIDE carries the following function designation(s):

CAS 95-96-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for LACTIDE

This page reproduces the CosIng inventory entry for LACTIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LACTIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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