Is OSAJIN safe to use in EU cosmetics?

OSAJIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 482-53-1?

CAS 482-53-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains OSAJIN?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8735715/10/2010

OSAJIN

4H,8H-Benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-

OSAJIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 482-53-1

CAS 482-53-1PubChem CID 95168

Osajin

Osajin is a member of isoflavanones. — ChEBI

IUPAC name: 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one

Molecular formula: C25H24O5
Molecular weight: 404.5 g/mol
Exact mass: 404.16237386 Da
XLogP3: 5.9
Topological polar surface area: 76.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

3'-DEOXYPOMIFERIN5'-O-DEMETHYLSCANDINONE83R5N9X74BNSC-215654H,8H-Benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano(2,3-h)chromen-4-oneRefChem:168645Osaiin

16 more reported names

5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-4H,8H-pyrano[2,3-f]chromen-4-oneUNII-83R5N9X74BNSC 21565Spectrum_000234SpecPlus_000197Spectrum2_000175Spectrum3_000225Spectrum4_001527Spectrum5_000034OSAJIN [MI]Oprea1_003228Oprea1_066678BSPBio_001869KBioGR_001934KBioSS_000714DivK1c_006293

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:7797
ChEMBL:CHEMBL238188
EPA DTXSID:DTXSID10964028
PubMed:22228954
PubMed:22087557
PubMed:21547262
PubMed:21532751
PubMed:21314138
PubMed:20706672
PubMed:19624015
PubMed:19394400
PubMed:18597965
PubMed:17969319
PubMed:17662606
PubMed:16936909

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for OSAJIN

INCI name

OSAJIN

Description

4H,8H-Benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-

Record provenance

Inventory reference: 87357
Imported identity: OSAJIN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for OSAJIN

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Key data

CAS

482-53-1

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#18472 · OSAJIN

Ingredients with overlapping formulation functions

ORYZA SATIVA SEED EXTRACTANTIOXIDANT, SKIN CONDITIONING

ORYZA SATIVA SEED PROTEINANTIOXIDANT

ORYZA SATIVA SEED PROTEIN EXTRACTANTIOXIDANT; SKIN CONDITIONING - MISCELLANEOUS

ORYZA SATIVA SEED WATERANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

OSMUNDA REGALIS LEAF EXTRACTANTIMICROBIAL, ANTIOXIDANT

OSTRYA JAPONICA LEAF EXTRACTANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

OVATODIOLIDEANTIMICROBIAL; ANTIOXIDANT; SKIN CONDITIONING - MISCELLANEOUS

OXALIS HEDYSAROIDES CALLUS CULTURE EXTRACTANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How OSAJIN appears in the CosIng inventory

The CosIng inventory lists OSAJIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

OSAJIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

OSAJIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, OSAJIN carries the following function designation(s):

ANTIOXIDANT

CAS 482-53-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for OSAJIN

This page reproduces the CosIng inventory entry for OSAJIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research OSAJIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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