What other records share CAS 197172-76-2?

CAS 197172-76-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8729415/10/2010

CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-α-aspartyl-D-phenylalanyl)

CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 197172-76-2

CAS 197172-76-2PubChem CID 9873475

Cyclotetrapeptide-24 aminocyclohexane carboxylate

IUPAC name: 2-[(9R,12S,18S)-9-benzyl-18-[3-(diaminomethylideneamino)propyl]-8,11,14,17,20-pentaoxo-7,10,13,16,19-pentazaspiro[5.14]icosan-12-yl]acetic acid

Molecular formula: C28H40N8O7
Molecular weight: 600.7 g/mol
Exact mass: 600.30199564 Da
XLogP3: -0.9
Topological polar surface area: 247.0 Å²
Hydrogen-bond donors: 8
Hydrogen-bond acceptors: 8
Covalent units: 1
Defined stereocentres: 3

Also known as

RefChem:1082794Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl)Cyclopeptide-5Cyclotetrapeptide-24 aminocyclohexane carboxylate [PCPC-DB]2-((9R,12S,18S)-9-Benzyl-18-(3-guanidinopropyl)-8,11,14,17,20-pentaoxo-7,10,13,16,19-pentaazaspiro[5.14]icosan-12-yl)acetic acidUNII-NR327745KQCYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE (PCPC-DB)Cyclopeptid-5

1 more reported name

CYCLO(1-AMINOCYCLOHEXANECARBONYL-L-ARGINYLGLYCYL-L-.ALPHA.-ASPARTYL-D-PHENYLALANYL)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL4650557

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording: peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

INCI name

CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

Description

Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-α-aspartyl-D-phenylalanyl)

Record provenance

Inventory reference: 87294
Imported identity: CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

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Key data

CAS

197172-76-2

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#7882 · CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

Ingredients with overlapping formulation functions

CYCLOPIA GENISTOIDES LEAF EXTRACTANTIOXIDANT

CYCLOPIA SUBTERNATA FLOWER/LEAF/STEM EXTRACTANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

CYCLOPROPYLBIMATOPROSTANTIOXIDANT

CYCLOPROPYLMETHYLBIMATOPROSTANTIOXIDANT

CYCLOVIROBUXINEANTIOXIDANT, BLEACHING

CYCNOCHES COOPERI EXTRACTANTIOXIDANT, SKIN CONDITIONING - EMOLLIENT

CYLINDROTHECA FUSIFORMIS EXTRACTANTIOXIDANT, SKIN PROTECTING

CYMBIDIUM ERYTHRAEUM FLOWER EXTRACTANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE appears in the CosIng inventory

The CosIng inventory lists CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE carries the following function designation(s):

ANTIOXIDANT

CAS 197172-76-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

This page reproduces the CosIng inventory entry for CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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