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InventoryRef 8573127/10/2010

DMSO

Dimethyl Sulfoxide

DMSO is linked to 1 EU annex record on this page. Inventory note: II/338.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence		1English
CanadaEvidence linked
Prohibited
Open this evidence		1English and French
New ZealandEvidence linked
Prohibited
Open this evidence		1English
ASEANEvidence linked
Prohibited
Open this evidence		1English and national languages
ChinaEvidence linked
Prohibited
Open this evidence		1Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Prohibited
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilEvidence linked
Prohibited
Open this evidence		1Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 67-68-5
CAS 67-68-5PubChem CID 679

Dimethyl Sulfoxide

Dimethyl sulfoxide is a 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. It has a role as a geroprotector, an alkylating agent, a non-narcotic analgesic, a MRI contrast agent, a polar aprotic solvent, a radical scavenger, an antidote and an Escherichia coli metabolite. It is a volatile organic compound and a sulfoxide. — ChEBI

IUPAC name
methylsulfinylmethane
Molecular formula
C2H6OS
Molecular weight
78.14 g/mol
Exact mass
78.01393598 Da
XLogP3
-0.6
Topological polar surface area
36.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

DMSOMethyl sulfoxideDimethyl sulphoxideDimethylsulfoxidesulfinylbismethaneDemasorbDomosoMethane, sulfinylbis-
16 more reported names
DemsodroxDromisolDeltanDemavetDemesoDolicurHyadurInfiltrinaSomiprontDimexideDurasorbSyntexanDermasorbDimethyl sulfur oxideDoligurDipirartril-tropico
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DMSO

INCI name

DMSO

Description

Dimethyl Sulfoxide

Record provenance

Inventory reference
85731
Imported identity
DMSO
Source update
27/10/2010
European Commission CosIng source notes

Key data

CAS
67-68-5
EC
200-664-3
Restriction
II/338
Function
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9568 · DMSO

Ingredients with overlapping formulation functions

DISODIUM C13-15 HYDROXY ALKANOYL/ISOALKANOYL GLUTAMATECLEANSING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING
DISODIUM SEBACATE/PALM KERNELATE TRIGLYCERIDECLEANSING, HAIR CONDITIONING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING
DITRIDECYL ADIPATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DITRIMETHYLOLPROPANE ISOSTEARATE/SEBACATEBINDING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DODECENEFRAGRANCE, SOLVENT, VISCOSITY CONTROLLING
ECHIUM PLANTAGINEUM SEED OILSKIN CONDITIONING, SOLVENT
EICOSANEFRAGRANCE, PERFUMING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
ERYTHRITYL TRIETHYLHEXANOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DMSO appears in the CosIng inventory

The CosIng inventory lists DMSO as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DMSO is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DMSO appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for DMSO reads: "II/338". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, DMSO carries the following function designation(s):

CAS 67-68-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DMSO

This page combines the CosIng inventory entry for DMSO with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research DMSO and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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