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CAS 1634-04-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8568115/10/2010

T-BUTYL METHYL ETHER

tert-butyl methyl ether

T-BUTYL METHYL ETHER is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1634-04-4

CAS 1634-04-4PubChem CID 15413

tert-Butyl methyl ether

Methyl tert-butyl ether (MTBE) is a flammable liquid with a distinctive, disagreeable odor. It is made from blending chemicals such as isobutylene and methanol, and has been used since the 1980s as an additive for unleaded gasolines to achieve more efficient burning.MTBE is also used to dissolve gallstones. Patients treated in this way have MTBE delivered directly to their gall bladders through special tubes that are surgically inserted. — Agency for Toxic Substances and Disease Registry (ATSDR)

IUPAC name: 2-methoxy-2-methylpropane

Molecular formula: C5H12O
Molecular weight: 88.15 g/mol
Exact mass: 88.088815002 Da
XLogP3: 0.9
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

Methyl tert-butyl etherMTBEMethyl t-butyl etherPropane, 2-methoxy-2-methyl-T-BUTYL METHYL ETHER2-Methyl-2-methoxypropaneMethyl tertiary-butyl etherEther, tert-butyl methyl

16 more reported names

Methyl 1,1-dimethylethyl ether1,1-dimethylethyl methyl etherCHEBI:2764229I4YB3S89TERT-BUTOXYMETHANEmethyl tert-butyl ether (mtbe)RefChem:8180822-methoxy-2-methyl propane216-653-1Methyl-tert-butyl etherMethyl-t-butyl ethertert-Butylmethyl ethertert-butylmethylether2-methoxy-2-methyl-propanetert-C4H9OCH3methyltert-butyl ether

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:27642
ChEMBL:CHEMBL1452799
EPA DTXSID:DTXSID3020833
PubMed:34121485
PubMed:29553459
PubMed:24128854
PubMed:22942756
PubMed:22833177
PubMed:22793027
PubMed:22783624
PubMed:22771234
PubMed:22767285
PubMed:22727754
PubMed:22717036
PubMed:22707826

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for T-BUTYL METHYL ETHER

INCI name

T-BUTYL METHYL ETHER

Description

tert-butyl methyl ether

Record provenance

Inventory reference: 85681
Imported identity: T-BUTYL METHYL ETHER
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for T-BUTYL METHYL ETHER

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Key data

CAS

1634-04-4

216-653-1

Restriction

—

Function

SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28350 · T-BUTYL METHYL ETHER

Ingredients with overlapping formulation functions

SUNFLOWEROYL METHYLGLUCAMIDECLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SOLVENT, SURFACTANT - CLEANSING

SWEET ALMOND OIL POLYGLYCERYL-4 ESTERSSOLVENT, SURFACTANT - CLEANSING

T-BUTYL ACETATESOLVENT

T-BUTYL ALCOHOLDENATURANT, PERFUMING, SOLVENT

TALLOLSKIN CONDITIONING - EMOLLIENT, SOLVENT

TETRADECENESKIN CONDITIONING - EMOLLIENT, SOLVENT, VISCOSITY CONTROLLING

TETRADECYLPROPIONATESSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

TETRAHYDROFURFURYL ACETATEFRAGRANCE, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How T-BUTYL METHYL ETHER appears in the CosIng inventory

The CosIng inventory lists T-BUTYL METHYL ETHER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

T-BUTYL METHYL ETHER is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

T-BUTYL METHYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, T-BUTYL METHYL ETHER carries the following function designation(s):

SOLVENT

CAS 1634-04-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for T-BUTYL METHYL ETHER

This page reproduces the CosIng inventory entry for T-BUTYL METHYL ETHER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research T-BUTYL METHYL ETHER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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