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InventoryRef 8532715/10/2010

ISORHAMNETIN

3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone

ISORHAMNETIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 480-19-3
CAS 480-19-3PubChem CID 5281654

Isorhamnetin

Isorhamnetin is a monomethoxyflavone that is quercetin in which the hydroxy group at position 3' is replaced by a methoxy group. It has a role as a metabolite, an anticoagulant and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a monomethoxyflavone, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is functionally related to a quercetin. It is a conjugate acid of an isorhamnetin(1-). ChEBI

IUPAC name
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
Molecular formula
C16H12O7
Molecular weight
316.26 g/mol
Exact mass
316.05830272 Da
XLogP3
1.9
Topological polar surface area
116.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
7
Covalent units
1
Defined stereocentres
0

Also known as

3-MethylquercetinIsorhamnetolQuercetin 3'-methyl ether3'-Methoxyquercetin3'-O-Methylquercetin3'-Methoxy-3,4',5,7-tetrahydroxyflavoneisorhamnetineiso-rhamnetin
16 more reported names
C.I. 756803,4',5,7-Tetrahydroxy-3'-methoxyflavone07X3IB4R4Z3,5,7,4'-Tetrahydroxy-3'-methoxyflavoneFLAVONE, 3,4',5,7-TETRAHYDROXY-3'-METHOXY-4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyroneCHEBI:60523,4',5,7-tetrahydroxy-3'-methoxy-flavone3-methyl-quercetinRefChem:5925207-545-53,6,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromone3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one3'-O-Methyl Quercetin3,5,7-Trihydroxy-2-(4-hydroxy-3-metoxyphenyl)benzopyran-4-one
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISORHAMNETIN

INCI name

ISORHAMNETIN

Description

3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone

Record provenance

Inventory reference
85327
Imported identity
ISORHAMNETIN
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How ISORHAMNETIN appears in the CosIng inventory

The CosIng inventory lists ISORHAMNETIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISORHAMNETIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISORHAMNETIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISORHAMNETIN carries the following function designation(s):

CAS 480-19-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for ISORHAMNETIN

This page reproduces the CosIng inventory entry for ISORHAMNETIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISORHAMNETIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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