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InventoryRef 8448215/10/2010

CHLOROFORM

Trichloromethane

CHLOROFORM is linked to 1 EU annex record on this page. Inventory note: II/366.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence		1English
CanadaEvidence linked
Prohibited
Open this evidence		1English and French
New ZealandEvidence linked
Prohibited
Open this evidence		1English
ASEANEvidence linked
Prohibited
Open this evidence		1English and national languages
ChinaEvidence linked
Prohibited
Open this evidence		1Chinese with selected English material
JapanEvidence linked
Prohibited
Open this evidence		1Japanese; official English translation available
South KoreaEvidence linked
Prohibited
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilEvidence linked
Prohibited
Open this evidence		1Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 67-66-3
CAS 67-66-3PubChem CID 6212

Chloroform

Chloroform is a one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines. It has a role as a central nervous system drug, an inhalation anaesthetic, a non-polar solvent, a carcinogenic agent and a refrigerant. It is a member of chloromethanes and a one-carbon compound. — ChEBI

IUPAC name
chloroform
Molecular formula
CHCl3
Molecular weight
119.37 g/mol
Exact mass
117.914383 Da
XLogP3
2.3
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

TrichloromethaneTrichlormethanTrichloroformFormyl trichlorideMethane, trichloro-Methenyl trichlorideMethyl trichlorideMethane trichloride
16 more reported names
ChloroformeCHCl3R 20 (Refrigerant)TriclorometanoCloroformioTrichloormethaanFreon 201,1,1-TrichloromethaneMethenyl chlorideRCRA waste number U044NCI-C02686ChloroformumChloroform bpHcc 20NSC-773617V31YC746X
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CHLOROFORM

INCI name

CHLOROFORM

Description

Trichloromethane

Record provenance

Inventory reference
84482
Imported identity
CHLOROFORM
Source update
15/10/2010
European Commission CosIng source notes
Annex II Restriction reference
Entry 366

Chloroform

CAS: 67-66-3
EC: 200-663-8

Key data

CAS
67-66-3
EC
200-663-8
Restriction
II/366
Function
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6224 · CHLOROFORM

Ingredients with overlapping formulation functions

CARBOXYMETHYL CAPROOYL CHITOSANABSORBENT, FILM FORMING, HUMECTANT, SOLVENT, SURFACTANT - CLEANSING
CASTOR OIL PROPANEDIOL ESTERSHAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT, SURFACTANT - EMULSIFYING
CD ALCOHOL 19SOLVENT, VISCOSITY CONTROLLING
CHLORINATED PARAFFINSKIN CONDITIONING, SKIN PROTECTING, SOLVENT, VISCOSITY CONTROLLING
CHLOROTRIFLUOROPROPENESOLVENT
COCOBUTYRAMIDO HYDROXYSULTAINECLEANSING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING, V…
COCONUT ALKANESSKIN CONDITIONING - EMOLLIENT, SOLVENT
COCOYL METHYL GLUCAMIDEHAIR CONDITIONING, SKIN CONDITIONING, SOLVENT, SURFACTANT - CLEANSING, VISCOSITY CONTROLLING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How CHLOROFORM appears in the CosIng inventory

The CosIng inventory lists CHLOROFORM as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CHLOROFORM is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CHLOROFORM appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CHLOROFORM reads: "II/366". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CHLOROFORM carries the following function designation(s):

CAS 67-66-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for CHLOROFORM

This page combines the CosIng inventory entry for CHLOROFORM with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CHLOROFORM and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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